Multi-organ characterisation of B-esterases in the European sea bass (Dicentrarchus labrax): Effects of the insecticide fipronil at two temperatures

Characterisation of Plasmatic B-Esterases in Bottlenose Dolphins (Tursiops Truncatus) and Their Potential as Biomarkers of Xenobiotic Chemical Exposures

“…It is likely that it could be originated in another tissue and then been transferred to the bloodstream. The finding on the lack of CE inhibition by BNPP in dolphin plasma, despite the ubiquitous presence of CE (Sanahuja et al, 2020) and consistently measurable hydrolysis rates in plasma, could be due to the buffering action of plasmatic albumin. This role of albumin has been described for other pesticides (Estevez and Vilanova, 2009) and chemicals such as TBBPA (Wang et al, 2014).…”

“…Mean ± SEM plasmatic hydrolysis rates of B-esterases (in nmol/min mL plasma) of several marine species using the same enzymatic protocol. 1 Own data unpublished in Caretta caretta; 2 data corresponding to Solea senegalensis in Sole et al, 2022); 3 data corresponding to Dicentrarchus labrax in Sanahuja et al (2020). In brackets number of analysis made (n).…”

“…In terrestrial mammals, all of the above mentioned enzymatic measures have been described in plasma (or serum) with highly species-dependent particularities, even within closely related mammals (Bahar et al, 2012;Li et al, 2005Li et al, , 2019Napon et al, 2018). Some of these measures have also been explored in fish (Sanahuja et al, 2020), turtles (Cortés-Gómez et al, 2018;Rivas-Hernández et al, 2018) and birds (Morcillo et al, 2018;Sogorb et al, 2007) using comparable methodologies, and have been mostly associated with neurotoxic chemicals.…”

Biomarker responses and metabolism in Lumbricus terrestris exposed to drugs of environmental concern, an in vivo and in vitro approach

“…Fipronil though dermal exposure did not affect any of the biomarkers tested in vivo or in vitro in earthworms after 48 h exposures. Former studies in fish, FIP administered via diet with the same chemical formulation was responsible for an oxidative stress condition and esterase modulation but the signs were not clearly manifested until 14 days food administration (Dallares et al,, 2020;Sanahuja et al, 2020). Nonetheless, larvae of the chironomid Chironomus J o u r n a l P r e -p r o o f riparius responded to FIP dosage after 48 h in terms of reduced GST and catalase but not AChE activity (Monteiro et al, 2019).…”

Global assessment of the response to chronic stress in European sea bass

“…In aquaculture, fish can be exposed to physical stressors (e.g. confinement, handling), or low water qualities all potentially altering fish welfare (Sanahuja et al, 2020;Sneddon et al, 2016;Toni et al, 2019). Most of welfare assessment are related to stress responses, experience of pain, growth problems, incidence of disease or abnormal behaviour (Sneddon et al, 2016;Stevens et al, 2017;Toni et al, 2019;van de Vis et al, 2020).…”