Multi-omics analysis uncovered systemic lupus erythematosus and COVID-19 crosstalk
Zekai Nian,
Yicheng Mao,
Zexia Xu
et al.
Abstract:Background
Studies have highlighted a possible crosstalk between the pathogeneses of COVID-19 and systemic lupus erythematosus (SLE); however, the interactive mechanisms remain unclear. We aimed to elucidate the impact of COVID-19 on SLE using clinical information and the underlying mechanisms of both diseases.
Methods
RNA-seq datasets were used to identify shared hub gene signatures between COVID-19 and SLE, while genome-wide association study dat… Show more
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