Multi-omics analysis reveals novel interplays between intratumoral bacteria and glioma
Ting Li,
Zhanyi Zhao,
Meichang Peng
et al.
Abstract:Emerging evidence highlights the potential impact of intratumoral microbiota on cancer. However, the microbial composition and function in glioma remains elusive. Consequently, our study aimed to investigate the microbial community composition in glioma tissues and elucidate its role in glioma development. We parallelly performed microbial profiling, transcriptome sequencing and metabolomics detection on tumor and adjacent normal brain tissues obtained from 50 glioma patients. We employed immunohistochemistry,… Show more
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