Multi-Omics analysis elucidates tumor microenvironment and intratumor microbes of angiogenesis subtypes in colon cancer
Yi Yang,
Yu-Ting Qiu,
Wen-Kun Li
et al.
Abstract:BACKGROUND
Angiogenesis plays an important role in colon cancer (CC) progression.
AIM
To investigate the tumor microenvironment (TME) and intratumor microbes of angiogenesis subtypes (AGSs) and explore potential targets for antiangiogenic therapy in CC.
METHODS
The data were obtained from The Cancer Genome Atlas database and Gene Expression Omnibus database. K-means clustering was used to construct the AGSs. The prognostic model was constructed based on the dif… Show more
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