Orange peel waste (OPW) is a byproduct generated in large quantities during the juice extraction process in the citrus industry. Due to its high content of bioactive compounds and organic matter, OPW has the potential to be used in various industrial applications, thus reducing the environmental impact associated with its disposal. One of the most promising applications of OPW is in the production of animal feed, where it can be used as a source of dietary fiber, pectin, and antioxidants. In addition, OPW can be used as a source of natural pigments and flavors in the food industry, particularly in the production of confectionery, bakery products, and beverages. Another potential application of OPW is in the production of biofuels and biochemicals. The high concentration of carbohydrates in OPW makes it a suitable substrate for the production of ethanol, which can be used as a fuel or a feedstock for the production of other chemicals. Furthermore, OPW can be used as a source of essential oils, which can be used in the fragrance and cosmetics industries. Other industrial applications of OPW include the production of biodegradable polymers, wastewater treatment, and the remediation of contaminated soils. However, the utilization of OPW in industrial applications is still limited by several factors, such as the high variability in composition and the lack of standardization in processing methods. In conclusion, OPW is a promising source of value-added products that can be used in various industrial applications. Further studies are needed to optimize the utilization of OPW and to overcome the challenges associated with its processing and standardization.