“…Algorithms used for liver segmentation include grey level evaluation [6,11,[24][25][26][27], clustering [17,[28][29][30], region-based method [31,32], Snakesbased method [33], grow-cut [34], graph cuts [15,[35][36][37], level set [16,[38][39][40][41], combinations of different approaches as for example Snakes and grow-cut [33], or graph cut and gradient flow active contour [5], or morphological operations and graph cuts [9,42], grey level and a priori knowledge like CT numbers and location [25], hidden Markov measure field model [18], multi-class smoothed Bayesian classification [20,21], and edge based methods [43]. The use of segmentation algorithm based on priority knowledge about appearance, shape and size of the liver [10,23,[44][45][46][47][48][49][50][51][52] and methods based on neural networks [53,54] have been also proposed.…”