Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis 1996
DOI: 10.1109/mmbia.1996.534053
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Multi-modality image registration by maximization of mutual information

Abstract: Mutual information of image intensities has been proposed as a iiew matching criterion for automated multimodality image registration. In this papel; we give experimental evidence of the power and the generality of the mutual information criterion by showing results for various applications involving C7: MR and PET images. Our results illustrate the large applicability of the approach and demonstrate its high suitability for routine use in clinical practice.

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Cited by 259 publications
(88 citation statements)
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References 12 publications
(8 reference statements)
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“…The objective function, called stack entropy in [6] and [7], measures the compactness of the intensity distribution for a certain voxel location across different subjects. Similar to the popular entropy based metrics used in pairwise registration (e.g., mutual information [8][9]), the current formulation of stack entropy considers image intensity as the only feature, and discards local contextual information that can be provided by the voxel neighborhood. Moreover, each voxel contributes equally to the metric, regardless of its anatomical properties.…”
Section: Introductionmentioning
confidence: 99%
“…The objective function, called stack entropy in [6] and [7], measures the compactness of the intensity distribution for a certain voxel location across different subjects. Similar to the popular entropy based metrics used in pairwise registration (e.g., mutual information [8][9]), the current formulation of stack entropy considers image intensity as the only feature, and discards local contextual information that can be provided by the voxel neighborhood. Moreover, each voxel contributes equally to the metric, regardless of its anatomical properties.…”
Section: Introductionmentioning
confidence: 99%
“…At each layer of the cascade, the classification is done through the estimation of mutual information [1] between the 3D model and the image. Mutual information has shown to be a robust metric for matching involving multimodal data [5,3].…”
Section: Mutual Information Computationmentioning
confidence: 99%
“…However, mutual information is only sensitive to gray-level distribution and does not include spatial information. Therefore, it fails in some multimodality co-registration methods [13] . For example, the gray levels of the PA and LS images characterize different functional information rather than spatial information.…”
mentioning
confidence: 99%
“…Mutual information is used as a feature matching (measures) criterion [13] , which measures the statistical dependence between two images A and B. It could be described by the following equations with entropy:…”
mentioning
confidence: 99%