Multi‐modality approach in curative local treatment of early rectal carcinomas

Hershman, M. J.; Myint, Arthur Sun; Makin, C. A.

doi:10.1046/j.1463-1318.2003.00502.x

Cited by 56 publications

(41 citation statements)

References 15 publications

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“…Though TEM produces similarly low recurrence rates as mentioned above, the evidence for its efficacy when compared with conventional surgery in terms of local control and survival has been affected by the fact that only 1% of all rectal cancers present as T 1 [62]. There are a few retrospective and case control studies as mentioned above, but only one randomised trial [25] directly comparing open radical surgery with TEM for pT 1 rectal cancer.…”

Section: Resultsmentioning

confidence: 99%

Transanal Endoscopic Microsurgery: Where Are We Now?

Maslekar¹,

Beral²,

White³

et al. 2006

Dig Surg

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Aims: This review of literature aimed to assess the role and establish the current status of transanal endoscopic microsurgery (TEM) in the management of benign and malignant rectal lesions. Methods: Areview of the literature was undertaken through the Medline database and by cross-referencing previous publications, thus identifying 54 relevant publications on TEM in the management of rectal lesions. Aggregated results of various parameters were calculated but statistical comparisons deemed unsuitable due to heterogeneity of data. Results: The TEM procedure is associated with good functional results, morbidity of 4% and zero procedure-related mortality. The local recurrence rates after TEM excision is 4.5% (range 0–14) for benign rectal lesions, 6% (0–13) for T₁ cancers, 14% (range 0–50) for T₂ cancers and 20% (range 14–67%) for T₃ cancers. Local recurrences after TEM can be surgically salvaged with good disease free survival rates. Conclusions: The TEM procedure clearly offers the benefits of good exposure of the operative field allowing extremely precise dissection and access to high rectal lesions unresectable by other methods. For pTis and low risk pT₁ lesions, the oncological results are comparable to the more traditional formal resection. The routine use of TEM for high-risk pT₁ and higher stage lesions is not an oncologically sound choice at the present moment.

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Section: Resultsmentioning

confidence: 99%

Transanal Endoscopic Microsurgery: Where Are We Now?

Maslekar¹,

Beral²,

White³

et al. 2006

Dig Surg

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“…These procedures have been usually performed in elderly, high-risk patients and in those who refuse permanent colostomy [1,2]. There are reports showing that recurrence and survival rates after local treatment are comparable to those after major surgery, and complication rates are lower and functional results better [1,3].…”

Section: Introductionmentioning

confidence: 99%

Long-term results of local excision for T1 rectal carcinoma: the experience of two colorectal units

et al. 2009

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“…Patients can be assessed by digital rectal examination supplemented by endoscopy and radiology [endorectal ultrasound or endorectal magnetic resonance imaging (MRI)]. Selection criteria and exclusion criteria for local treatment are summarized in table 3 and 4 (Hershman et al, 2003). Various local treatment options available will be discussed in the following paragraphs.…”

Section: Managementmentioning

confidence: 99%