Abstract:Morphology is an essential phenotype in the characterization of cells and their states, as it is closely related to cell function. Recent advances like Patch-seq enable simultaneously profiling the morphology, gene expression, and physiological properties of individual cells. However, computational methods that can summarize the great diversity of complex cell morphologies found in tissues and infer associations with other single-cell data modalities remain scarce. Here we report a computational framework, nam… Show more
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