Multi-level System Coupling of Error Commission, Detection and Correction in the Error Monitoring and Processing System are Required for High Precision Task Performance, and Modulates Neural Plasticity through Changes in Glucoallostasis

Neurometaplasticity: Glucoallostasis control of plasticity of the neural networks of error commission, detection, and correction modulates neuroplasticity to influence task precision

“…Glucoallostasis regulates the malleability of the neural circuitry dedicated to error commission, detection and correction. We have discussed the mechanisms of glucoallostasis regulation of error commission, detection and correction [3,4]. This regulatory impact of glucoallostasis on this neural circuitry also modulates neuroplasticity of brain regions involved in error commission, detection and correction such as the left posterior parietal cortex, medial prefrontal cortex, anterior cingulate cortex, and mesolimbic dopaminergic system [3,4,[47][48][49].…”

“…We have discussed the mechanisms of glucoallostasis regulation of error commission, detection and correction [3,4]. This regulatory impact of glucoallostasis on this neural circuitry also modulates neuroplasticity of brain regions involved in error commission, detection and correction such as the left posterior parietal cortex, medial prefrontal cortex, anterior cingulate cortex, and mesolimbic dopaminergic system [3,4,[47][48][49]. Error commission, error detection and error correction functions of these brain regions are measured physiologically by feedback-related negativity (FN) and error-related negativity (ERN) [48,50,51].…”

“…In a recent work, we suggested that glucoallostasis is essential for the control of plasticity of the error monitoring and processing system (EMPS). The EMPS refers to a monitoring response system diffusely located in several brain regions including the mediofrontal cortex, and plays an essential role in error commission, detection and correction [3,4]. Error commission, detection and correction form integral products of the overall activities of EMPS.…”

“…In many cases, however, task precision is affected by the level of error commission, which decreases the quality of work or task performance. But error commission is an integral component of the EMPS that is substantially modulated by both plastic events and glucoallostasis [3,4]. In our previous work, we suggested that both glucoallostasis and plasticity play some roles in the control of the activities of the neural networks of EMPS.…”