Multi-height micro structures in poly(dimethyl siloxane) lab-on-a-chip

Abstract

The PDMS (poly(dimethyl siloxane)) replica molding is very useful for lab-on-a-chip development. This paper describes the several fabrication schemes of master fabrication for multi-height micro structures in PDMS microchip, and gives the overview over the technologies used for PDMS replica molding and channel closing with oxygen plasma treatment. Developed processes in the paper are good solution to fabricate the more complex structures in microfluidic lab-on-a-chip.

Separation of three water‐soluble vitamins by poly(dimethylsiloxane) microchannel electrophoresis with electrochemical detection

“…The sample was injected into the separation channel using a cross arrangement. The carbon fiber microcolumn working electrode was home-made according to the procedure described in previous work [17,28]. With the help of a XTB-1 microscope (Jiangnan Optical Instrument Factory, Nanjing, China) the position of the working electrode was adjusted easily by a 3-D adjustor (Shanghai Lianyi Instrument Factory of Optical Fiber and Laser, Shanghai, China) and inserted into the channel by about 40 lm.…”