Multi-genome synteny detection using minimizer graph mappings
Lauren Coombe,
Parham Kazemi,
Johnathan Wong
et al.
Abstract:In recent years, the landscape of reference-grade genome assemblies has seen substantial diversification. With such rich data, there is pressing demand for robust tools for scalable, multi-species comparative genomics analyses, including detecting genome synteny, which informs on the sequence conservation between genomes and contributes crucial insights into species evolution. Here, we introduce ntSynt, a scalable utility for computing large-scale multi-genome synteny blocks using a minimizer graph-based appro… Show more
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