Multi-Functional Therapeutic Active Extract of Marine Asterias rubens against Tooth Decay Pathogen

Abstract

Today, childhood caries is main health related disease it affects many schooling children in many countries especially developed by lactic acid bacteria. So in this present the isolating the 50 lactic acid bacteria from different decay affected children’s in Fen Dental Clinic, Tirupur Dt. The emerging bacteria LAB confirmed by phenotype and genotype characterization. After, the pathogen screened for the production of biofilm for to check the resistant mechanism of the Lactobacillus acidophilus. In this study the MTLA1-50 isolates produced strong biofilm were confirmed for the Lactobacillus acidophilus carrying resistant capability. In particularly, the maximum strong biofilm producing strains MTLA32 and MTLA50 followed by other isolates. Due to pre-dominant resistant activity immediately need innovative drug to eliminate biofilm. Currently star fish extract play a vital role in eliminating the bacterial biofilm for this motive in this study chosen the star fish extract in the concentration of 50, 100, 150µl was performed and executed by well diffusion techniques. The results showed the strain No. MTLA32 and MTLA 50 got the maximum zone of inhibition at 150µl (52mm and 38mm) of extract. Hence this research paper proved the star fish extract has a powerful anti-therapeutic medicine mechanism to treat the dental pathogen. 
 Keywords: Star Fish Extract, Dental Caries, Biofilm Production.