Multi-detector CT-colonography in inflammatory bowel disease: Prospective analysis of CT-findings to high-resolution video colonoscopy

Andersen, Kjel; Vogt, Christoph; Blondin, D.; Beck, Andreas; Heinen, W.; Aurich, Volker; Häussinger, Dieter; Mödder, Ulrich; Cohnen, Mathias

doi:10.1016/j.ejrad.2005.11.004

Cited by 60 publications

(33 citation statements)

References 28 publications

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“…CTC enables visualization of infl ammatory polyps, cobblestoning, and longitudinal ulcers. [6][7][8] In the present study, Crohn's disease was the third most common disease found by CTC. Two patients with Crohn's disease underwent CTC twice for follow-up, and it revealed improved colonic fi ndings and complications after treatment.…”

Section: Discussionmentioning

confidence: 93%

“…[6][7][8] According to a study of 33 patients with Crohn's disease, comparing CTC, barium enema, and conventional colonoscopy, CTC was superior to barium enema and conventional colonoscopy in terms of its ability to visualize the proximal site of the stenosis. 7 CT air enema results resemble those of conventional barium enema and is useful for evaluating the overall deformity of the colon and stenosis in patients with IBD.…”

Section: Discussionmentioning

confidence: 98%

“…CTC can be performed, however, in patients in whom it is not contraindicated, those who are not able to complete conventional colonoscopy, and those with infl ammatory bowel disease (IBD). [6][7][8] There is consensus that it can be applied for colorectal cancer screening and staging, but there is not yet a consensus on its application for patients with noncolorectal cancerous conditions. Our purpose was to assess the performance of CTC in patients whose indication for CTC was not to screen for or stage colorectal cancer.…”

Section: Introductionmentioning

confidence: 99%

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Initial experience with computed tomographic colonography applied for noncolorectal cancerous conditions

et al. 2011

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Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

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Initial experience with computed tomographic colonography applied for noncolorectal cancerous conditions

et al. 2011

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“…Active inflammatory colitis has been shown to correlate with thickening of the colon wall to greater than 5 mm on CTC [93]. A small, blinded prospective study (n = 21) in a cohort of IBD patients found sensitivities of 64% and 100% for acute and chronic inflammation, respectively, with specificities of 75% and 100%, respectively [94]. It is uncertain whether CTC can differentiate Crohn's colitis from CUC.…”

Section: Ct Colonography (Virtual Colonoscopy)mentioning

confidence: 98%

Current and future diagnostic approaches: From serologies to imaging

Loftus

2007

Curr Gastroenterol Rep

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Advances in serologic markers and imaging modalities continue to revolutionize diagnostic approaches to inflammatory bowel disease (IBD). Autoimmune and antimicrobial antibodies demonstrate diagnostic value in those patients with a moderate pretest probability of disease. Emerging data also support the use of antimicrobial antibody levels as a predictive tool for small bowel complications and the need for future surgery. In addition to being a prognostic marker in patients with acute severe colitis, serum C-reactive protein has been shown to correlate with clinical, endoscopic, and radiologic measures of disease activity. Capsule endoscopy and double-balloon endoscopy allow for visualization of the entire small bowel, and double-balloon endoscopy also has the capability to treat lesions. CT enterography is beginning to replace small bowel follow-through because of its high sensitivity and specificity for disease of the small intestine. Both CT and magnetic resonance enterography detect luminal and extraluminal abnormalities, with MRI serving as a safe imaging option in cases of pregnancy and renal insufficiency. These newer modalities add to the armamentarium clinicians can use for evaluation of IBD.

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“…Individual CT features (bowel wall thickening, hyperenhancement, mural stratification, mesenteric hyperemia, pericolonic stranding and enlarged lymph nodes), as well as the cumulative CT score (sum of inflammatory parameters), demonstrated statistically significant correlation with colonoscopic severity using the Mayo UC score ( P < 0.0001); however, under CT examination, only intestinal wall thickening correlated with histopathological severity scores ( P = 0.01) [16]. A small study of UC patients ( n = 6) assessed using CTC demonstrated moderate correlation between loss of haustration, a rigid bowel wall and bowel thickness with UC endoscopic severity [17]. …”

Section: Computed Tomographymentioning

confidence: 99%

Radiographical evaluation of ulcerative colitis

Deepak

2014

Gastroenterology Report

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Radiographical modalities have become important diagnostic tools in cases of ulcerative colitis (UC). Imaging can be used non-invasively to determine the extent of involvement, severity of disease and to detect disease-related complications and extra-intestinal inflammatory bowel disease (IBD) manifestations. While abdominal X-rays and barium enemas still retain their relevance in specific clinical settings, the use of computed tomography enterography (CTE) or magnetic resonance enterography (MRE) are now used as first-line investigations to exclude active small bowel disease in IBD patients and can be utilized to detect active colonic inflammation. Additionally, CT colonography and MR colonography are emerging techniques with potential applications in UC. Ultrasonography, leukocyte scintigraphy and positron emission tomography are novel abdominal imaging modalities currently being explored for IBD interrogations. This plethora of radiological imaging options has become a vital component of UC assessments.

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Multi-detector CT-colonography in inflammatory bowel disease: Prospective analysis of CT-findings to high-resolution video colonoscopy

Cited by 60 publications

References 28 publications

Initial experience with computed tomographic colonography applied for noncolorectal cancerous conditions

Initial experience with computed tomographic colonography applied for noncolorectal cancerous conditions

Current and future diagnostic approaches: From serologies to imaging

Radiographical evaluation of ulcerative colitis

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