Multi‐country outbreak of Salmonella Enteritidis phage type 8, MLVA profile 2‐9‐7‐3‐2 and 2‐9‐6‐3‐2 infections
Abstract:A multi-country outbreak of Salmonella Enteritidis phage type (PT) 8 with multiple locus variablenumber tandem repeat analysis (MLVA) profiles 2-9-7-3-2 and 2-9-6-3-2, linked to eggs, is ongoing in the EU/EEA. Based on whole genome sequencing (WGS), isolates are part of two distinct but related genetic clusters. ECDC and EFSA are liaising with relevant authorities in the Member States and the European Commission to facilitate the coordination of investigation and response measures. From 1
“…Animal food products are implicated in human Salmonella infection outbreaks related to local and multinational food distribution networks (Dallman et al, 2016;EFSA & ECDP, 2017;Zenner et al, 2014), and international in-flight catering (Rebolledo et al, 2014). The isolation of Campylobacter strains from chicken carcases similar to those frequently isolated in humans is not uncommon and signifies the importance of animals in human infections (Devane et al, 2013;Nielsen et al, 2006;Stone et al, 2013).…”
Section: Sources Of Infections Related To Foods Of Animal Originmentioning
Livestock meat and offal contribute significantly to human nutrition as sources of high‐quality protein and micronutrients. Livestock products are increasingly in demand, particularly in low‐ and middle‐income settings where economies are growing and meat is increasingly seen as an affordable and desirable food item. Demand is also driving intensification of livestock keeping and processing. An unintended consequence of intensification is increased exposure to zoonotic agents, and a contemporary emerging problem is infection with Campylobacter and Salmonella spp. from livestock (avian and mammalian), which can lead to disease, malabsorption and undernutrition through acute and chronic diarrhoea. This can occur at the farm, in households or through the food chain. Direct infection occurs when handling livestock and through bacteria shed into the environment, on food preparation surfaces or around the house and surroundings. This manuscript critically reviews Campylobacter and Salmonella infections in animals, examines the factors affecting colonization and faecal shedding of bacteria of these two genera as well as risk factors for human acquisition of the infection from infected animals or environment and analyses priority areas for preventive actions with a focus on resource‐poor settings.
“…Animal food products are implicated in human Salmonella infection outbreaks related to local and multinational food distribution networks (Dallman et al, 2016;EFSA & ECDP, 2017;Zenner et al, 2014), and international in-flight catering (Rebolledo et al, 2014). The isolation of Campylobacter strains from chicken carcases similar to those frequently isolated in humans is not uncommon and signifies the importance of animals in human infections (Devane et al, 2013;Nielsen et al, 2006;Stone et al, 2013).…”
Section: Sources Of Infections Related To Foods Of Animal Originmentioning
Livestock meat and offal contribute significantly to human nutrition as sources of high‐quality protein and micronutrients. Livestock products are increasingly in demand, particularly in low‐ and middle‐income settings where economies are growing and meat is increasingly seen as an affordable and desirable food item. Demand is also driving intensification of livestock keeping and processing. An unintended consequence of intensification is increased exposure to zoonotic agents, and a contemporary emerging problem is infection with Campylobacter and Salmonella spp. from livestock (avian and mammalian), which can lead to disease, malabsorption and undernutrition through acute and chronic diarrhoea. This can occur at the farm, in households or through the food chain. Direct infection occurs when handling livestock and through bacteria shed into the environment, on food preparation surfaces or around the house and surroundings. This manuscript critically reviews Campylobacter and Salmonella infections in animals, examines the factors affecting colonization and faecal shedding of bacteria of these two genera as well as risk factors for human acquisition of the infection from infected animals or environment and analyses priority areas for preventive actions with a focus on resource‐poor settings.
“…MLVA-профили штаммов меняются достаточно быстро, что позволяет идентифицировать клоны и дифференцировать эпидемические штаммы при расследовании вспышек [8,11,13,16,17]. В странах Евросоюза и США метод MLVA широко используется при расследовании вспышек, в том числе международных, вызванных штаммами двух ведущих серотипов (S.Enteritidis, S.Typhimurium), для субтипирования которых разработаны стандартизированные протоколы [18][19][20][21][22][23][24][25]. По сравнению с PFGE этот метод имеет большую разрешающую способность.…”
Section: мультилокусное Vntr-типирование (Multiple Locus Variable Numunclassified
В обзоре представлены методы молекулярного субтипирования (серотипирование, MLST, PFGE, MLVA, WGS) изолятов Salmonella spp., использующиеся в рамках эпидемиологического надзора и при расследовании случаев групповой заболеваемости сальмонеллезами. Отражена методическая основа и степень внедрения этих методов в работу лабораторий в мире. Особое внимание уделено методам субтипирования, основанным на данных полногеномного секвенирования, и существующим международным платформам для анализа данных "Pathogene Detection" и "Enterobase".
“…In many countries (e.g., United States, United Kingdom, Uruguay, Lebanon), S. Enteritidis is ranked as the most common serovar responsible for human infections ( 5 – 8 ). In the past few years, large-scale multinational outbreaks of S. Enteritidis were reported ( 9 – 13 ). From 2017 to 2020, a multistate outbreak of S. Enteritidis in Europe resulted in 656 confirmed cases ( 14 ).…”
Salmonella enterica
serovar Enteritidis is a leading cause of foodborne infections. We previously developed a genomic typing database (MGTdb) for
S.
Enteritidis to facilitate global surveillance of this pathogen.
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