Multi-channel electrical bioimpedance: a non-invasive method to simultaneously measure cardiac output and individual arterial limb flow in patients with cardiovascular disease

Stanley, Alfred W.H.; Herald, Jeffery W.; Athanasuleas, Constantine L.; Jacob, Saji; Bartolucci, Alfred A.; Tsoglin, Alexander N.

doi:10.1007/s10877-009-9189-5

Cited by 4 publications

(3 citation statements)

References 19 publications

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“…In addition to conventional bioimpedance measurement methods using four electrodes, multiple channel devices have been advised for use in precise bioimpedance measurements (Vondra et al 2006, Stanley et al 2009. Electrical impedance tomography (EIT) and magnetic induction methods have also been studied in monitoring respiration and cardiac function based on impedance changes in the thorax (Steffen et al 2007, Grant et al 2011.…”

Section: Discussionmentioning

confidence: 99%

Bioimpedance-based measurement method for simultaneous acquisition of respiratory and cardiac gating signals

Koivumäki¹,

Vauhkonen²,

Kuikka³

et al. 2012

Physiol. Meas.

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Respiratory and cardiac motion artefacts impair the quality and reliability of medical imaging, particularly in nuclear medicine. At worst, the interpretation of distorted images may lead to inadequate or unnecessary treatment. Image artefacts can be minimized by gating the image acquisition according to respiratory phase and cardiac contractions. However, currently there are no clinically established dual-gating methods in nuclear medicine imaging. The aim of this study is to validate a previously determined optimized bioimpedance measurement configuration against traditional respiratory and cardiac measurement systems in 12 volunteers. High agreement and excellent correlations (r = 0.944-0.999) were found between respiratory peak-to-peak amplitudes as well as temporal respiratory and cardiac intervals. Above all, good quality respiratory and cardiac gating signals were obtained from all test subjects with a fairly regular sinus rhythm. Importantly, both signals were acquired simultaneously with a single device. Due to the simplicity of this inexpensive method, the technique has high potential to be adopted for dual-gating in clinical practice in the future.

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Section: Discussionmentioning

confidence: 99%

Bioimpedance-based measurement method for simultaneous acquisition of respiratory and cardiac gating signals

Koivumäki¹,

Vauhkonen²,

Kuikka³

et al. 2012

Physiol. Meas.

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show abstract

“…They found high correlations between change and percent change in SV obtained by 2D echocardiography with the change and percent change in both the maximum amplitude of and area beneath forearm Z(t), respectively (r = 0.78-0.86). Stanley et al (2009) obtained Z(t) from the transthoracic approach and upper and lower extremities. Waveform amplification clearly shows that the maximum systolic upslope (acceleration) from the thorax and upper extremities are identical.…”

Section: Discussionmentioning

confidence: 99%

Stroke volume obtained by electrical interrogation of the brachial artery: transbrachial electrical bioimpedance velocimetry

et al. 2012

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The goal of this study is to measure left ventricular stroke volume (SV) from the brachial artery (BA) using electrical bioimpedance. Doppler-derived SV was used for comparison. Twenty-nine healthy adults were recruited for study. Doppler echocardiographic-derived SV was obtained from the product of distal left ventricular outflow tract cross-sectional area and systolic velocity integral. SV from the BA was obtained by transbrachial electrical bioimpedance velocimetry (TBEV). Application of a current field across the left brachium was effected by injection of a constant magnitude, high frequency, low amperage, alternating current. Therein, a static voltage (U(0)) and pulsatile voltage change (ΔU(t)) were measured and converted to their corresponding impedances, Z(0) and ΔZ(t). TBEV-derived SV was obtained by multiplying a square root value of the normalized, acceleration-based, peak first time derivative of ΔZ(t) by a volume conductor and systolic flow time. Inter-method agreement was determined by the Bland-Altman method. To assess the contribution of blood resistivity variations to ΔZ(t), BA diameters were measured at end-diastole and peak systolic expansion. Results indicate that since the BA demonstrates parabolic, laminar flow, with minimal diameter changes, blood resistivity variations are likely responsible for the derived impedance changes. Bland-Altman analysis shows that SV is obtainable by TBEV from healthy humans at rest.

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“…There are several multi-channel bioimpedance measurement devices published in the literature [12][13][14][15]. Most of these publications focus either on the measurement setup itself or on the measurement of the voltage drop across the bioimpedance and the following signal processing.…”

Section: Introductionmentioning

confidence: 99%

Galvanically Decoupled Current Source Modules for Multi-Channel Bioimpedance Measurement Systems

2017

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Abstract:Bioimpedance measurements have become a useful technique in the past several years in biomedical engineering. Especially, multi-channel measurements facilitate new imaging and patient monitoring techniques. While most instrumentation research has focused on signal acquisition and signal processing, this work proposes the design of an excitation current source module that can be easily implemented in existing or upcoming bioimpedance measurement systems. It is galvanically isolated to enable simultaneous multi-channel bioimpedance measurements with a very low channel-coupling. The system is based on a microcontroller in combination with a voltage-controlled current source circuit. It generates selectable sinusoidal excitation signals between 0.12 and 1.5 mA in a frequency range from 12 to 250 kHz, whereas the voltage compliance range is ±3.2 V. The coupling factor between two current sources, experimentally galvanically connected with each other, is measured to be less than −48 dB over the entire intended frequency range. Finally, suggestions for developments in the future are made.

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Multi-channel electrical bioimpedance: a non-invasive method to simultaneously measure cardiac output and individual arterial limb flow in patients with cardiovascular disease

Abstract: MEB accurately measures cardiac output in patients with moderate to severe clinical heart failure and accurately measures regional arterial limb flow in patients with peripheral arterial disease.

Cited by 4 publications

References 19 publications

Bioimpedance-based measurement method for simultaneous acquisition of respiratory and cardiac gating signals

Bioimpedance-based measurement method for simultaneous acquisition of respiratory and cardiac gating signals

Stroke volume obtained by electrical interrogation of the brachial artery: transbrachial electrical bioimpedance velocimetry

Galvanically Decoupled Current Source Modules for Multi-Channel Bioimpedance Measurement Systems

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