Multi-Channel Bioimpedance System for Detecting Vascular Tone in Human Limbs: An Approach

Hammoud, Ahmad; Tikhomirov, Alexey; Myasishcheva, Galina; Shaheen, Zein; Volkov, A. K.; Briko, Andrey; Щукин, С. И.

doi:10.3390/s22010138

Cited by 16 publications

(10 citation statements)

References 29 publications

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“…Further, to evaluate lung blood flow, we used the following parameters: RI—rheographic index of the right pulmonary arterial system, which indirectly indicates the level of blood filling into the pulmonary artery during right ventricle blood output; DCI—dicrotic index, which is an indirect indication of the vascular tone in pulmonary artery large vessels; and DSI—diastolic index, which helps to characterize the ratio of venous drainage to arterial blood supply in the right lung [ 35 ]. While no changes were found in RI between the face immersion attempts, DCI and DSI were significantly lower during the face submersion at attempts #1 and #2 but not at attempt #3 ( Table 2 ).…”

Section: Resultsmentioning

confidence: 99%

“…A relative index of skin capillary blood flow in the left index finger was recorded by a photoplethysmogram (PPG). The pulmonary artery rheogram was recorded by the impedance method for the investigation of right pulmonary artery blood flow (RPABF) [ 35 , 57 , 58 ], and the following physiological parameters were used for the evaluation: stroke output (SO, mL), rheographic index (RI, Ohm; reflects the lung tissue blood filling), dicrotic index (DCI, %; reflects the vascular tone of resistant vessels of the pulmonary artery system), and diastolic index (DSI, %; reflects the ratio of venous drainage to arterial blood supply).…”

Section: Methodsmentioning

confidence: 99%

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Vascular Reactions of the Diving Reflex in Men and Women Carrying Different ADRA1A Genotypes

Baranova

Podyacheva

Zemlyanukhina

et al. 2022

IJMS

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The diving reflex is an oxygen-saving mechanism which is accompanied by apnea, reflex bradycardia development, peripheral vasoconstriction, spleen erythrocyte release, and selective redistribution of blood flow to the organs most vulnerable to lack of oxygen, such as the brain, heart, and lungs. However, this is a poorly studied form of hypoxia, with a knowledge gap on physiological and biochemical adaptation mechanisms. The reflective sympathetic constriction of the resistive vessels is realized via ADRA1A. It has been shown that ADRA1A SNP (p.Arg347Cys; rs1048101) is associated with changes in tonus in vessel walls. Moreover, the Cys347 allele has been shown to regulate systolic blood pressure. The aim of this work was to evaluate whether the ADRA1A polymorphism affected the pulmonary vascular reactions in men and women in response to the diving reflex. Men (n = 52) and women (n = 50) untrained in diving aged 18 to 25 were recruited into the study. The vascular reactions and blood flow were examined by integrated rheography and rheography of the pulmonary artery. Peripheral blood circulation was registered by plethysmography. The ADRA1A gene polymorphism (p.Arg347Cys; rs1048101) was determined by PCR-RFLP. In both men and women, reflective pulmonary vasodilation did occur in response to the diving reflex, but in women this vasodilation was more pronounced and was accompanied by a higher filling of the lungs with blood.. Additionally, ADRA1A SNP (p.Arg347Cys; rs1048101) is associated with sex. Interestingly, women with the Arg347 allele demonstrated the highest vasodilation of the lung vessels. Therefore, our data may help to indicate women with the most prominent adaptive reactions to the diving reflex. Our data also indicate that women and men with the Cys allele of the ADRA1A gene polymorphism have the highest risk of developing lung hypertension in response to the diving reflex. The diving reflex is an oxygen-saving mechanism which is accompanied by apnea, reflex bradycardia development, peripheral vasoconstriction, spleen erythrocyte release, and selective redistribution of blood flow to the organs most vulnerable to lack of oxygen, such as the brain, heart, and lungs. However, this is a poorly studied form of hypoxia, with a knowledge gap on physiological and biochemical adaptation mechanisms.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Vascular Reactions of the Diving Reflex in Men and Women Carrying Different ADRA1A Genotypes

Baranova

Podyacheva

Zemlyanukhina

et al. 2022

IJMS

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“…Hammoud et al [ 56 ] presented an approach for determining vascular tone in human extremities based on multi-channel bioimpedance measurements. Vascular tone plays a vital role in regulating blood pressure and coronary circulation, and it determines the peripheral vascular resistance.…”

Section: Vascular Diseasesmentioning

confidence: 99%

Cardiovascular diseases diagnosis by impedance cardiography

Mansouri

Alharbi

Alshrouf

et al. 2022

Journal of Electrical Bioimpedance

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Cardiovascular disease (CVD) represents the leading cause of mortality worldwide. In order to diagnose CVDs, there are a range of detection methods, among them, the impedance cardiography technique (ICG). It is a non-invasive and low-cost method. In this paper, we highlight recent advances and developments of the CDVs diagnosis mainly by the ICG method. We considered papers published during the last five years (from 2017 until 2022). Based on this study, we expressed the need for an ICG database for the different CDVs.

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“…Bioimpedance methods such as impedance plethysmography (IPG) and impedance cardiography (ICG) are non‐invasive, convenient and low‐cost methods widely used for several different diagnosis purposes, including vascular and cardiovascular diseases 6,7,8,9,10 . Shash et al investigated the effect of vascular diseases such as stenosis and aneurysm on the bioimpedance measurements by developing simple mathematical models 11 .…”

Section: Introductionmentioning

confidence: 99%

“…The results showed a correlation between the aforementioned diseases with the measured bioimpedance in the

β

dispersion range frequency to differentiate between normal and diseased blood vessels. Hammoud et al presented an approach to determine the vascular tone type and its temporal and spatial changes in all segments of human limbs 12 . The approach shows the potential of a multi‐channel system in providing information about blood circulation through different arteries.…”

Section: Introductionmentioning

confidence: 99%

Monitoring of false lumen thrombosis in type B aortic dissection by impedance cardiography – A multiphysics simulation study

Badeli

Jafarinia

Melito

et al. 2022

Numer Methods Biomed Eng

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Aortic dissection is caused by a tear on the aortic wall that allows blood to flow through the wall layers. Usually, this tear involves the intimal and partly the medial layer of the aortic wall. As a result, a new false lumen develops besides the original aorta, denoted then as the true lumen. The local hemodynamic conditions such as flow disturbances, recirculations and low wall shear stress may cause thrombus formation and growth in the false lumen. Since the false lumen status is a significant predictor for late-dissection-related deaths, it is of great importance in the medical management of patients with aortic dissection. The hemodynamic changes in the aorta also alter the electrical conductivity of blood. Since the blood is much more conductive than other tissues in the body, such changes can be identified with non-invasive methods such as impedance cardiography. Therefore, in this study, the capability of impedance cardiography in monitoring thrombosis in the false lumen is studied by multiphysics simulations to assist clinicians in the medical management of patients under treatment.To tackle this problem, a 3D computational fluid dynamics simulation has been set up to model thrombosis in the false lumen and its impact on the blood flow-induced conductivity changes. The electrical conductivity changes of blood have been assigned as material properties of the blood-filled aorta in a 3D finite element electric simulation model to investigate the impact of conductivity changes on the measured impedance from the body's surface.The results show remarkable changes in the electrical conductivity distribution in the measurement region due to thrombosis in the false lumen, which significantly impacts the morphology of the impedance cardiogram. Thus, frequent † Vahid Badeli and Alireza Jafarinia contributed equally to this work

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Multi-Channel Bioimpedance System for Detecting Vascular Tone in Human Limbs: An Approach

Cited by 16 publications

References 29 publications

Vascular Reactions of the Diving Reflex in Men and Women Carrying Different ADRA1A Genotypes

Vascular Reactions of the Diving Reflex in Men and Women Carrying Different ADRA1A Genotypes

Cardiovascular diseases diagnosis by impedance cardiography

Monitoring of false lumen thrombosis in type B aortic dissection by impedance cardiography – A multiphysics simulation study

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