Multi-center evaluation of the Research Use Only NeuMoDx monkeypox virus (MPXV) fully automated real-time PCR assay
Heba H. Mostafa,
Gavin Wall,
Szu-Chi Su
et al.
Abstract:The mpox outbreak, caused by monkeypox virus (MPXV), accelerated the development of molecular diagnostics. In this study, we detail the evaluation of the Research Use Only (RUO) NeuMoDx MPXV assay by multiple European and US sites. The assay was designed and developed by Qiagen for the NeuMoDx Molecular Systems. Primers and probes were tested for specificity and inclusivity
in silico
. The analytical sensitivity of the assay was determined by testing dilutions of synthetic and genom… Show more
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