Multi-biomarker responses in the freshwater mussel Dreissena polymorpha exposed to polychlorobiphenyls and metals

Faria, Melissa; Carrasco, Luís; Dı́ez, Sergi; Riva, Maria Carmen; Bayona, Josep M.; Barata, Carlos

doi:10.1016/j.cbpc.2008.07.012

Cited by 74 publications

(55 citation statements)

References 69 publications

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“…GSH is a major non-protein thiol that can serve as both a substrate for conjugation with xenobiotics and as an antioxidant to protect cellular components from oxidative stress (Larose et al, 2008;Faria et al, 2009). As with other species such as mullet (Thomas and Wofford, 1984), snakehead (Rana et al, 1995) and matrinxã (Monteiro et al, 2010), we observed increased hepatic GSH levels at all Hg concentrations in the liver of fl ounder.…”

Section: Tissue-specifi C Oxidative Responses Of Fi Sh To Hg Exposuresupporting

confidence: 46%

Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury

Huang

Cao

et al. 2012

Chin. J. Ocean. Limnol.

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Section: Tissue-specifi C Oxidative Responses Of Fi Sh To Hg Exposuresupporting

confidence: 46%

Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury

Huang

Cao

et al. 2012

Chin. J. Ocean. Limnol.

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“…Significantly higher elevation in metallothioneins compared to that observed in the pristine area was apparent for dreissenids from three harbours (H1, H3, H4), while moderate rise in EROD activity (by 70-and 35%, respectively) was recorded in two harbours (H1, H4). Although EROD activity assessment in bivalves was considered a disputable method in outlining exposure to organic chemicals (Viarengo et al, 2007), we have included this endpoint based on evidences of significant induction of CYP-like enzymes and associated mixed function oxidase components in mussels either in in situ studies (de Lafontaine et al, 2000;Binelli et al, 2005;Okay et al, 2014) or laboratory experiments (Faria et al, 2009;Martin-Diaz et al, 2009;Sapone et al, 2016). Our results outlined just moderate spatial and temporal variability in the EROD activity of dreissenids inhabiting the investigated sites therefore, we considered for the moment these results as inconclusive.…”

Section: Discussionmentioning

confidence: 99%

Interspecies comparison of selected pollution biomarkers in dreissenid spp. inhabiting pristine and moderately polluted sites

Farkas

Ács

Vehovszky

et al. 2017

Science of The Total Environment

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Stress biomarkers, which can outline impacts of contaminants in aquatic biota at the biochemical level, are increasingly used as early warning tools in environmental monitoring. Reliable biomarker based assessment schemes, however, request appropriate knowledge of baseline levels of selected endpoints, and the potential influence of a range of natural influencing factors (both abiotic and biotic) as well. In this study, we examined the interspecies variability of various biomarkers (metallothioneins (MT), ethoxyresorufin-Odeethylase activity (EROD), lipid peroxidation (LPO), DNA strand breaks (DNA_sb), vitellogenin-like proteins (Vtg)) in Dreissena polymorpha and Dreissena bugensis inhabiting either pristine-or moderately impacted sites of Lake Balaton (Hungary). Levels of all biomarkers considered revealed low interspecies variability in the two dreissenid species at all sampling sites, with consistently higher (but statistically insignificant) values in Dreissena polymorpha. Levels of all biomarkers varied within the two investigated seasons, with significant influence of the reproduction cycle particularly on the levels of metallothioneins and vitellogenin-like proteins. Each biomarker considered was elevated by October, with significantly higher values in the mussels inhabiting harbours. Insignificant spatial and temporal variability in the general health indicators (condition index, total protein content) of dreissenids was observed, which, in parallel with evident rise in biomarker levels, apparently suggest that the anthropogenic impacts in harbours affect mussel fitness yet at sub organismal level. Our data might serve useful basis for future environmental monitoring surveys, especially in habitats where the progressive replacement of Dreissena polymorpha by Dreissena bugensis is taking place, as the interspecies variability in susceptibility to chemical stress of the two species is well comparable.

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“…Field and lab studies also demonstrated that metals can increase or decrease the activities of antioxidant enzymes in freshwater zebra mussels (Faria et al 2009). Peña-Llopis et al (2002) found that impaired glutathione redox status was associated with decreased survival in organophosphate -poisoned marine bivalves.…”

Section: Environmental Hazard Assessmentmentioning

confidence: 96%

“…Most biochemical determinations have been described and characterized previously (Faria et al 2009). Hereafter we only provide a brief description.…”

Section: Biochemical Determinationsmentioning

confidence: 99%

Identifying major pesticides affecting bivalve species exposed to agricultural pollution using multi-biomarker and multivariate methods

et al. 2010

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The aim of this investigation was to identify major pesticides that may cause detrimental effects in bivalve species affected by agricultural pollution. Investigations were carried out using freshwater clams (Corbicula fluminea) transplanted in the main drainage channels that collect the effluents coming from agriculture fields in the Ebro Delta (NE Spain) during the main growing season of rice (from May to August). Environmental hazards were assessed by measuring simultaneous up 46 contaminant levels and 9 biomarker responses. Measured biological responses showed marked differences across sites and months. Antioxidant and esterase enzyme responses were in most cases inhibited. Lipid peroxidation levels increased steadily from May in upstream stations to August in drainage channels. Principal Component (PCA) and Partial Least Squares to Latent Structure regression (PLS) analyses allowed the identification of endosulfan, propanil, and phenylureas as being the chemical contaminants causing the most adverse effects in the studied species.

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Multi-biomarker responses in the freshwater mussel Dreissena polymorpha exposed to polychlorobiphenyls and metals

Cited by 74 publications

References 69 publications

Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury

Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury

Interspecies comparison of selected pollution biomarkers in dreissenid spp. inhabiting pristine and moderately polluted sites

Identifying major pesticides affecting bivalve species exposed to agricultural pollution using multi-biomarker and multivariate methods

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