2011
DOI: 10.1002/jcb.23224
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Multi-biomarker pattern for tumor identification and prognosis

Abstract: In last decades, the basic, clinical, and translational research efforts have been directed to the identification of standard biomarkers associated with the degree of malignancy. There is an increasingly public health concern for earlier detection of cancer development at stages in which successful treatments can be achieved. To meet this urgent clinical demand, early stage cancer biomarkers supported by reliable and robust experimental data that can be readily applicable in the clinical practice, are required… Show more

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Cited by 29 publications
(25 citation statements)
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“…However, in the present study, the COX-2 inhibitor NS-398 did not significantly inhibit the proliferation of cholangiocarcinoma cells in vitro. This finding is similar to those in previous reports of COX-2 expression and function at different stages of cholangiocarcinoma (Wu et al, 2010;Yoon et al, 2010;Rodriguez-Enriquez et al, 2011;Schoppmann et al, 2011). On the other hand, COX-2 inhibitors have been confirmed as effective auxiliary drugs for cholangiocarcinoma (Murmu, 2014;Zabron et al, 2013).…”
Section: Discussionsupporting
confidence: 93%
“…However, in the present study, the COX-2 inhibitor NS-398 did not significantly inhibit the proliferation of cholangiocarcinoma cells in vitro. This finding is similar to those in previous reports of COX-2 expression and function at different stages of cholangiocarcinoma (Wu et al, 2010;Yoon et al, 2010;Rodriguez-Enriquez et al, 2011;Schoppmann et al, 2011). On the other hand, COX-2 inhibitors have been confirmed as effective auxiliary drugs for cholangiocarcinoma (Murmu, 2014;Zabron et al, 2013).…”
Section: Discussionsupporting
confidence: 93%
“…Serum tumor markers are widely applied in the diagnosis, treatment effect assessment and disease monitoring [ 12 ]. Up to date, a series of studies have explored the diagnostic and prognostic value of various serum tumor markers for gastric cancer [ 5 ].…”
Section: Discussionmentioning
confidence: 99%
“…Serum tumor markers are widely used for diagnosis, treatment effect assessment, and disease monitoring. 9 However, few studies have explored the diagnostic value of tumor markers for PC in ascites fluid. Some researchers have argued that peritoneal fluid carcinoembryonic antigen (CEA) has predictive value for PC and prognostic value in colorectal cancer.…”
Section: Introductionmentioning
confidence: 99%