Multi-biomarker approach to assess the acute effects of cerium dioxide nanoparticles in gills, liver and kidney of Oncorhynchus mykiss

Correia, Alberto Teodorico; Rodrigues, Sara; Ferreira-Martins, Diogo; Ribeiro, Maria Inês; Antunes, Sara C.

doi:10.1016/j.cbpc.2020.108842

Cited by 15 publications

(9 citation statements)

References 65 publications

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“…To date, the estimated production of nCeO 2 is around 1000 tons/year and it has become one of the most produced ENPs in the world (Piccino et al, 2012). Upon their release into the aquatic environment, nCeO 2 may provoke adverse effects to various organisms (Rundle et al, 2016;Taylor et al, 2016;Kosak Née Röhder et al, 2018;Wang and Nowack, 2018;Correia et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Effects of humic substances on the aqueous stability of cerium dioxide nanoparticles and their toxicity to aquatic organisms

Wang

Zhai

et al. 2021

Science of The Total Environment

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Section: Introductionmentioning

confidence: 99%

Effects of humic substances on the aqueous stability of cerium dioxide nanoparticles and their toxicity to aquatic organisms

Wang

Zhai

et al. 2021

Science of The Total Environment

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“…(2016) , which indicated the 96-hour LC 50 value of MCLE to be at 127 mg/L. In this present study, a sub-lethal toxicity test was performed to determine the histological changes on gills, liver and kidney of African catfish after exposure to MCLE for 96 h, as according to Correia et al . (2020) , with slight modifications.…”

Section: Methodsmentioning

confidence: 94%

Histopathological Alterations in Gills, Liver and Kidney of African Catfish (Clarias gariepinus, Burchell 1822) Exposed to Melaleuca cajuputi Extract

Marina Hassan,

Anuar Abdalah Nagi Melad,

Mohd Ihwan Zakariah

et al. 2023

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This study evaluated the histopathological changes in the gill, liver and kidney of African catfish (Clarias gariepinus) intoxicated with a sub-lethal dose of Melaleuca cajuputi leaves extract (MCLE) for 96 h. The acute toxicity test has been determined previously with a value of 96-h LC50 = 127 mg/L, hence the selection of sub-lethal ranges from 60 mg/L to 160 mg/L of MCLE. Degenerative alterations were prominent in all tested organs, particularly after exposure to a high concentration of MCLE. Gill exhibited haemorrhage, epithelial lifting, lamellar disorganisation, and necrosis after exposure to a high MCLE concentration. Alterations in the liver include congestion, hydropic degeneration, and vacuolation, whereas lesions in the kidney were pyknosis, vacuolation, hydropic degeneration, and tubular necrosis. The obtained data showed that the organs experienced severe changes proportional to the increase in MCLE concentration. In addition, fish exposed to higher concentrations than the LC50 value experienced irreversible lesions. The present study suggests that the use of MCLE below the LC50 is recommended to avoid severe alterations to organs, particularly in African catfish. This study demonstrated that the use of MCLE above the LC50 promotes severe damage to the gills, liver and kidney of African catfish. However, further investigations are needed to define the causing-mechanisms underlying these effects.

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“…Anyhow, the mechanism of oxidative stress in the treatments resulted fairly different depending on the different coatings. Regarding the Naked CeO 2 NPs, the induction of GPx activity is probably due to an excess of H 2 O 2 content generated by the NPs (Correia et al, 2020). This excess could also be responsible for the inhibition of CAT activity (Regoli et al, 2011).…”

Section: Influence Of Surface Coating On Ceo 2 Nps Toxicity To Musselsmentioning

confidence: 99%

Coating with polysaccharides influences the surface charge of cerium oxide nanoparticles and their effects to Mytilus galloprovincialis

Nigro

Freitas

Maggioni³

et al. 2021

NanoImpact

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Multi-biomarker approach to assess the acute effects of cerium dioxide nanoparticles in gills, liver and kidney of Oncorhynchus mykiss

Cited by 15 publications

References 65 publications

Effects of humic substances on the aqueous stability of cerium dioxide nanoparticles and their toxicity to aquatic organisms

Effects of humic substances on the aqueous stability of cerium dioxide nanoparticles and their toxicity to aquatic organisms

Histopathological Alterations in Gills, Liver and Kidney of African Catfish (Clarias gariepinus, Burchell 1822) Exposed to Melaleuca cajuputi Extract

Coating with polysaccharides influences the surface charge of cerium oxide nanoparticles and their effects to Mytilus galloprovincialis

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