Mucous Gland Adenoma Simulating Bronchial Asthma: Case Report and Literature Review

Milenković, Branislava; Stojšić, Jelena; Mandaric, D.; Stevic, Ruza

doi:10.1080/02770900701645371

Cited by 20 publications

(11 citation statements)

References 14 publications

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“…[1,3] We could only find 35 cases of MGA that have been reported. The first case of "bronchial adenoma arising in mucous glands" was described by Ramsey and Reimann [4] in 1953.…”

Section: Discussionmentioning

confidence: 85%

“…The duration of symptoms prior to diagnosis varied from a few weeks to 10 years, with prolonged symptoms being usual. [1,5,6] The presenting symptoms in our case are typical for an endobronchial polypoid tumor. The polypoid growth is more likely to obstruct the lumen and can cause recurrent pneumonia.…”

Section: Discussionmentioning

confidence: 86%

“…The polypoid growth is more likely to obstruct the lumen and can cause recurrent pneumonia. [1,6] The symptoms of an endobronchial tumor primarily depend on mechanical factors rather than on the pathologic characteristics of the tumor itself. Furthermore, the diagnosis of these tumors is not always easy.…”

Section: Discussionmentioning

confidence: 99%

“…[3] Nevertheless, some authors have pointed out the malignant proliferative potential of the tumor. [1,3,[5][6][7] Four cases of malignant proliferative changes of the tumor [7] and two cases of recurrence after local excision [5] have so far been reported. [7] There was no tumor recurrence in the outpatient 15 months after the surgery.…”

Section: Discussionmentioning

confidence: 99%

“…[1] This type of tumor is truly benign. It can cause obstruction and hemoptysis, but it doesn't extend below the cartilaginous layer of the bronchial wall, and there is no invasive growth or metastasis.…”

mentioning

confidence: 99%

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Mucous gland adenoma of the bronchus: a case report

Yaran¹

2012

Turk Gogus Kalp Dama

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Müköz bezi adenomu, çoğunlukla trakeobronşiyal seromü-sinöz bezi ve duktusların son derece nadir, benign, egzofitik bir tümörüdür. Bu yazıda, başlangıçta pnömoni olarak değerlendirilen, sol üst lob bronşundan kaynaklanan bir müköz bezi adenomu olgusu literatür incelemesi eşliğinde sunuldu.Anah tar söz cük ler: Benign; bronş adenomu; müköz bezi adenomu.Mucous gland adenoma is an extremely rare, benign, predominantly exophytic tumor of the tracheobronchial seromucinous glands and ducts. In this article, we report a case of mucous gland adenoma arising from the left upper lobe bronchus, which was initially misdiagnosed as pneumonia in the light of literature review.Key words: Benign; bronchial adenoma; mucous gland adenoma. Mucous gland adenoma (MGA) is an extremely rare tumor that arises from the bronchial mucous glands and usually presents as pedunculated or sessile polyps in the lumen of larger bronchi.[1] This type of tumor is truly benign. It can cause obstruction and hemoptysis, but it doesn't extend below the cartilaginous layer of the bronchial wall, and there is no invasive growth or metastasis.[2] We present a case of MGA arising from the left upper bronchus which was successfully treated by surgical resection. CASE REPORTA 52-year-old man was admitted to our hospital with a three-month history of atelectasis and recurrent pneumonitis of the left upper lobe in June of 2008. He had a productive cough but no hemoptysis at the time of admission. His past history was unremarkable. He smoked 72 packs of cigarettes a year until two months prior to his admission. The physical examination was normal. A chest X-ray revealed left upper lobe atelectasis and a hilar density with a fluffy infiltrate adjacent to its periphery (Figure 1a). Chest computed tomography (CT) showed an obstructive lesion in the left upper lobe bronchus (Figure 1b). A bronchoscopic examination revealed a pedunculated papillary lesion obstructing the apicoposterior segment of the left upper lobe bronchus. A biopsy specimen was suggestive of bronchial mucosa and showed severe squamous dysplasia. A left upper lobectomy and mediastinal lymph node dissection was performed via posterolateral thoracotomy in June of 2008. Postoperative pathologic examination identified mucus gland adenoma of the bronchus. The postoperative course was complete and uneventful. Fifteen months after the surgery, there was no sign of tumor relapse, and the patient was asymptomatic.In the pathologic findings, a gross examination of the left upper lobe revealed that the apicoposterior segment bronchus was occluded by a polypoid, wellcircumscribed mass of approximately 1.1 cm in diameter. The tumoral mass projected into the lumen and attached to the bronchial wall with a broad base. The lymph nodes showed reactive inflammatory changes.A microscopic examination revealed a tumor prominent into the bronchial lumen that was covered by regular respiratory epithelial cells. The tumor, composed of glandular structures, was partially surrounded by mucinous epithelium (Figure 2a). Gla...

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“…[1,3] We could only find 35 cases of MGA that have been reported. The first case of "bronchial adenoma arising in mucous glands" was described by Ramsey and Reimann [4] in 1953.…”

Section: Discussionmentioning

confidence: 85%

Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%