Abstract:RESUMEN: La mucositis oral (MO) es la reacción secundaria aguda más frecuente en la cavidad oral y tracto gastrointestinal en pacientes oncológicos sometidos a quimioterapia o radioterapia de cabeza y cuello que incide negativamente en la calidad de vida del paciente. Su tratamiento requiere de un manejo multidisciplinario con el objetivo de minimizar la incidencia y severidad de esta patología. El desconocimiento parcial respecto de su etiopatogenia imposibilita la realización de protocolos para el manejo de … Show more
“…Oral mucositis (OM) is one of the most common complications of non-surgical cancer treatments, which results from chemotherapy (CT) and/or radiotherapy (RT) 1 . This pathology is characterized by complications such as erythema, edema, oral ulcerations, dysphagia, odynophagia, taste alterations, phonation difficulties, and pain, among other manifestations, with pain being of high importance, as a result of analgesic and/or nutritional requirements, which entail great impacts on quality of life due to a higher risk of infections associated with the release of free radicals, which induce the proliferation of microorganisms and bacterial pathogens that enhance the process of inflammation and epithelial degradation [2][3][4][5][6][7] .…”
Oral mucositis (OM) affects children and young people with cancer treatment, where low-level laser therapy (LLLT) has been suggested as a preventive method. The objective of this article was to analyze, by means of a synopsis, the effects of LLLT on the prevention and treatment of the clinical picture of OM in a pediatric cancer population treated with radiotherapy and/ or chemotherapy. An electronic search of systematic reviews published between 2018 and 2021 was performed in the Medline database, Epistemonikos metasearch engine, and the Google Scholar registry. The search strategy was "low-level light therapy AND oral mucositis AND pediatric patient". Two hundred and seventy-three articles were found, analyzing two systematic reviews. LLLT was shown to reduce the risk of OM (OR = 0.50, 95% CI, 0.29 to 0.87), improving the clinical picture on the 7 th day (RR = 0.90, 95% CI = 0.46-1.78) with few adverse events. LLLT seems to reduce the risk of OM and the severity of the condition, although more studies are required to identify an optimal dose.
“…Oral mucositis (OM) is one of the most common complications of non-surgical cancer treatments, which results from chemotherapy (CT) and/or radiotherapy (RT) 1 . This pathology is characterized by complications such as erythema, edema, oral ulcerations, dysphagia, odynophagia, taste alterations, phonation difficulties, and pain, among other manifestations, with pain being of high importance, as a result of analgesic and/or nutritional requirements, which entail great impacts on quality of life due to a higher risk of infections associated with the release of free radicals, which induce the proliferation of microorganisms and bacterial pathogens that enhance the process of inflammation and epithelial degradation [2][3][4][5][6][7] .…”
Oral mucositis (OM) affects children and young people with cancer treatment, where low-level laser therapy (LLLT) has been suggested as a preventive method. The objective of this article was to analyze, by means of a synopsis, the effects of LLLT on the prevention and treatment of the clinical picture of OM in a pediatric cancer population treated with radiotherapy and/ or chemotherapy. An electronic search of systematic reviews published between 2018 and 2021 was performed in the Medline database, Epistemonikos metasearch engine, and the Google Scholar registry. The search strategy was "low-level light therapy AND oral mucositis AND pediatric patient". Two hundred and seventy-three articles were found, analyzing two systematic reviews. LLLT was shown to reduce the risk of OM (OR = 0.50, 95% CI, 0.29 to 0.87), improving the clinical picture on the 7 th day (RR = 0.90, 95% CI = 0.46-1.78) with few adverse events. LLLT seems to reduce the risk of OM and the severity of the condition, although more studies are required to identify an optimal dose.
“…La mucositis oral (MO) es una de las complicaciones más comunes en los tratamientos oncológicos no quirúrgicos, producto de la quimioterapia (QT) y/o radioterapia (RT) 1 . Esta patología se caracteriza por presentar complicaciones como: eritema, edema, ulceraciones orales, disfagia, odinofagia, alteraciones del gusto, dificultades de fonación y dolor entre otras manifestaciones, siendo el dolor de gran importancia, producto del requerimiento analgésico y/o nutricional que conlleva a grandes impactos sobre la calidad de vida a causa de los mayores riesgos de infecciones asociadas a la liberación de radicales libres, que inducen la proliferación de microorganismos y patógenos bacterianos potenciadores del proceso de inflamación y degradación epitelial [2][3][4][5][6][7] .…”
La mucositis oral (MO) afecta a niños y jóvenes con tratamiento oncológico, donde se ha sugerido la terapia láser de baja potencia (o LLLT por sus siglas en inglés) como método preventivo. El objetivo de este trabajo fue analizar mediante una sinopsis, los efectos de la LLLT sobre la prevención y tratamiento del cuadro clínico de MO en población pediátrica oncológica tratada con radioterapia y/o quimioterapia. Se realizó una búsqueda electrónica de revisiones sistemáticas publicadas entre 2018 y 2021 en la base de datos Medline, metabuscador Epistemonikos y registro Google Académico. La estrategia de búsqueda fue "low-level light therapy AND oral mucositis AND pediatric patient". Se encontraron 273 artículos, analizándose dos revisiones sistemáticas. La LLLT mostró disminuir el riesgo de MO (OR = 0.50, IC 95%, 0.29 a 0.87) mejorando el cuadro clínico al séptimo día (RR= 0.90, IC 95%, 0.46 a 1.78) con pocos eventos adversos. La LLLT parece disminuir el riesgo de MO y la gravedad del cuadro, aunque se requieren de más estudios para identificar una dosis óptima.
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