Mucosal leishmaniasis due to Leishmania (Viannia) panamensis in Colombia: clinical characteristics.

Abstract

The Leishmaniases are a group of diseases whose clinical presentation is in part determined by the infecting species. Until recently, mucosal leishmaniasis was attributed exclusively to Leishmania (Viannia ) braziliensis; however, the capacity of other species of the subgenus Viannia to invade mucosal tissue has been documented. This report examines the clinical characteristics of 23 parasitologically diagnosed patients with mucosal leishmaniasis due to L. (V.) panamensis from the Pacific Coast of Colombia seen at CIDEIM between 1985 and 1996. Most of the mucosal lesions 74% (17 of 23) were mild, with a short time of evolution (median ϭ 2.5 months) and were present concomitantly with an active cutaneous lesion in 61% (14 of 23) of the cases. The simultaneous presentation of mucosal and active cutaneous lesions contrast with classical descriptions of mucosal leishmaniasis caused by L. (V.) braziliensis, and highlights the importance of early diagnosis of mucosal disease by the examination of mucosa in all cases of cutaneous leishmaniasis.

Epidemiology of leishmaniasis in Ecuador: current status of knowledge - A review

“…MCL originating from the Pacific or Andean regions has never been recorded , Armijos et al 1997. This is surprising, as Osorio et al (1998) reported MCL among residents of the Colombian Pacific coast caused by the same species circulating in this Ecuadorian region.…”

Real-Time PCR Assay for Detection and Quantification of Leishmania (Viannia) Organisms in Skin and Mucosal Lesions: Exploratory Study of Parasite Load and Clinical Parameters

“…Clinical presentation and outcome of ATL are associated with the host immune response and the infecting Leishmania species (1,2). Among the different parasite species causing cutaneous leishmaniasis (CL) in the New World, Leishmania (Viannia) braziliensis is considered the most important because of its prevalence, its difficulty to cure, its public health importance, and the risk of severe disease, i.e., disfiguring mucosal leishmaniasis (ML) (2)(3)(4)(5)(6).…”

Las células de Langerhans en la inmunidad a leishmaniasis.

“…Por su parte, Leishmania (V) panamensis es la especie del parásito responsable del 95%, aproximadamente, de los casos que se registran en el país; produce principalmente LCL y, también, casos de LCD y LM (5,6). Además, L. (V) panamensis se caracteriza por producir infecciones crónicas y persistentes y está implicada también en la presentación de recaídas, reinfecciones y diseminación a mucosas (7,8).…”