Mucosal incision‐assisted biopsy versus endoscopic ultrasound‐guided fine‐needle aspiration with a rapid on‐site evaluation for gastric subepithelial lesions: A randomized cross‐over study

Osoegawa, Takashi; Minoda, Yosuke; Ihara, Eikichi; Komori, Keishi; Aso, Akira; Goto, Ayako; Itaba, Soichi; Ogino, Hitoshi; Nakamura, Kazuhiko; Harada, Naohiko; Makihara, Kosuke; Tsuruta, Satoshi; Yamamoto, Hidetaka; Ogawa, Yoshihiro

doi:10.1111/den.13367

Cited by 35 publications

(62 citation statements)

References 25 publications

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“…Mucosal incision-assisted biopsy (MIAB) is powerful method for the diagnosis of subepithelial lesions [20,21]; we might have tried MIAB after EUS-FNA failure, but the patient's symptom got worse, and hence, we decided to have surgery. e lesion was located from the antrum of stomach to the bulbus of duodenum across the pylorus, and distal gastrectomy was selected for the treatment instead of laparoscopic and endoscopic cooperative surgery (LECS) [22].…”

Section: Discussionmentioning

confidence: 99%

A Case of Myoepithelial Hamartoma: Morphological Variation Supported by OCT4 Expression

Tanaka

Nishida

Iwamuro

et al. 2021

Case Reports in Gastrointestinal Medicine

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In this report, we describe a patient with myoepithelial hamartoma, which is regarded as synonymous with adenomyosis and heterotopic pancreas. Endoscopy revealed a submucosal tumor in the antrum of the stomach. Subsequently, distal gastrectomy with Roux-en-Y reconstruction was performed. Histological findings of adenomyomatous lesion and heterotopic pancreatic tissue were observed in this lesion. The distribution of OCT4, which is a pluripotency marker, varied in each part.

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Section: Discussionmentioning

confidence: 99%

A Case of Myoepithelial Hamartoma: Morphological Variation Supported by OCT4 Expression

Tanaka

Nishida

Iwamuro

et al. 2021

Case Reports in Gastrointestinal Medicine

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“…Alternative endoscopic approaches may include mucosal incision-assisted biopsy (MIAB) using the technique of endoscopic submucosal dissection (ESD) or endoscopic mucosal resection (EMR). MIAB has been shown to have similar diagnostic accuracy and safety to EUS-FNA with ROSE [50].…”

Section: Tissue Acquisition For Pathological Diagnosismentioning

confidence: 97%

“…EUS-guided fine needle aspiration (EUS-FNA) is safe and useful for pathological diagnosis, although the rate of tissue acquisition of EUS-FNA for GISTs and SMTs varies dependent on the tumor, location, and skill of the specialist, and is lower than that for pancreatic lesions [46][47][48]. The diagnostic accuracy of EUS-FNA may be improved by the introduction of rapid on-site evaluation (ROSE) [49,50]. Recently, EUS-guided biopsy sampling (EUS-FNB), equipped with the side-fenestrated reverse bevel design needle, was shown to be more reliable in obtaining sufficient tissue (91%) from pancreatic cancer than EUS-FNA (67%) [51].…”

Section: Tissue Acquisition For Pathological Diagnosismentioning

confidence: 99%

Recent Progress and Challenges in the Diagnosis and Treatment of Gastrointestinal Stromal Tumors

Nishida

Yoshinaga²,

Takahashi

et al. 2021

Cancers

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Gastrointestinal stromal tumors (GISTs) are the most frequent malignant mesenchymal tumors in the gastrointestinal tract. The clinical incidence of GISTs is estimated 10/million/year; however, the true incidence is complicated by frequent findings of tiny GISTs, of which the natural history is unknown. The initial work-up with endoscopy and endoscopic ultrasonography plays important roles in the differential diagnosis of GISTs. Surgery is the only modality for the permanent cure of localized GISTs. In terms of safety and prognostic outcomes, laparoscopy is similar to laparotomy for GIST treatment, including tumors larger than 5 cm. GIST progression is driven by mutations in KIT or PDGFRA or by other rare gene alterations, all of which are mutually exclusive. Tyrosine kinase inhibitors (TKIs) are the standard therapy for metastatic/recurrent GISTs. Molecular alterations are the most reliable biomarkers for TKIs and for other drugs, such as NTRK inhibitors. The pathological and genetic diagnosis prior to treatment has been challenging; however, a newly developed endoscopic device may be useful for diagnosis. In the era of precision medicine, cancer genome profiling by targeted gene panel analysis may enable potential targeted therapy even for GISTs without KIT or PDGFRA mutations.

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“…3). The usefulness of this technique, termed mucosal cutting biopsy (MCB) or mucosal incision-assisted biopsy (MIAB), has been reported in several articles (Table 1), [59][60][61][62][63][64][65][66][67][68][69] many of which are retrospective, single-arm analyses with a relatively small number of cases. In approximately 20 mm in size, the diagnostic yield of MCB/MIAB for gastric SETs shows 86.9% in 314 lesions, ranging from 60% to 100% among the articles.…”

Section: Mucosal Cutting Biopsy/mucosal Incision-assisted Biopsymentioning

confidence: 99%

Advancements in the Diagnosis of Gastric Subepithelial Tumors

2022

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A diagnosis of subepithelial tumors (SETs) is sometimes difficult due to the existence of overlying mucosa on the lesions, which hampers optical diagnosis by conventional endoscopy and tissue sampling with standard biopsy forceps. Imaging modalities, by using computed tomography and endoscopic ultrasonography (EUS) are mandatory to noninvasively collect the target's information and to opt candidates for further evaluation. Particularly, EUS is an indispensable diagnostic modality for assessing the lesions precisely and evaluating the possibility of malignancy. The diagnostic ability of EUS appears increased by the combined use of contrast-enhancement or elastography. Histology is the gold standard for obtaining the final diagnosis. Tissue sampling requires special techniques to break the mucosal barrier. Although EUS-guided fine-needle aspiration (EUS-FNA) is commonly applied, mucosal cutting biopsy and mucosal incision-assisted biopsy are comparable methods to definitively obtain tissues from the exposed surface of lesions and seem more useful than EUS-FNA for small SETs. Recent advancements in artificial intelligence (AI) have a potential to drastically change the diagnostic strategy for SETs. Development and establishment of noninvasive methods including AI-assisted diagnosis are expected to provide an alternative to invasive, histological diagnosis.

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Mucosal incision‐assisted biopsy versus endoscopic ultrasound‐guided fine‐needle aspiration with a rapid on‐site evaluation for gastric subepithelial lesions: A randomized cross‐over study

Cited by 35 publications

References 25 publications

A Case of Myoepithelial Hamartoma: Morphological Variation Supported by OCT4 Expression

A Case of Myoepithelial Hamartoma: Morphological Variation Supported by OCT4 Expression

Recent Progress and Challenges in the Diagnosis and Treatment of Gastrointestinal Stromal Tumors

Advancements in the Diagnosis of Gastric Subepithelial Tumors

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