Mucor dimorphism.

Orlowski, Michael

doi:10.1128/mmbr.55.2.234-258.1991

Cited by 115 publications

(62 citation statements)

References 184 publications

(381 reference statements)

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“…Yeast-like cells of M. rouxii can be developed from sporangiospores by controlling the conditions under which they are cultured (Orlowski, 1991). In this study, the addition of PEA and oxygen limitation were used to induce the yeast-like growth of M. rouxii.…”

Section: Effect Of Culture Conditions On Morphology and Growth Of Mucmentioning

confidence: 99%

Comparative fatty acid profiling ofMucor rouxiiunder different stress conditions

Jeennor

Laoteng

Tanticharoen

et al. 2006

FEMS Microbiology Letters

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To understand the relationship between fatty acid metabolism and the growth morphology of Mucor rouxii, fatty acid profiling was studied comparatively in cells grown under conditions which included different atmospheric conditions or the addition of phenethyl alcohol (PEA). The significant difference in fatty acid profiles from M. rouxii grown under aerobic or anaerobic conditions was not found to be directly related to morphological growth. Oxygen limitation, which induced the formation of pure multipolar budding yeasts, led to a decrease in long-chain fatty acids-- particularly unsaturated fatty acids-- and an increase in medium-chain saturated fatty acids, a finding which contrasted with the aerobic cultures, including mycelia and PEA-induced bipolar budding cells. High levels of C18 : 1Delta(9) were found in aerobic yeast cultures with additional PEA when compared to that in the aerobically grown mycelia. The identification of unusual fatty acids in Mucor in response to alcoholic and hypoxic stresses - including odd-numbered fatty acids and 7-hydroxy dodecanoic acid (7-OH C12 : 0) in addition to the more common fatty acids - implied that an important role existed for these unusual fatty acids.

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Section: Effect Of Culture Conditions On Morphology and Growth Of Mucmentioning

confidence: 99%

Comparative fatty acid profiling ofMucor rouxiiunder different stress conditions

Jeennor

Laoteng

Tanticharoen

et al. 2006

FEMS Microbiology Letters

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“…The aggregation of Dictyostelium ce\ls into fruit bodies is caused by lack of nutrients (Jacobson and Lodish, 1975). Lack of nitrogen stimulates the development of peritheciae and ascospores in Neurospora crassa (Schmit and Brody, 1976), Also, the lack of a fermentable carbon source favours hyphal growth of Muco/"species (Orlowski, 1991).…”

Section: Introductionmentioning

confidence: 99%

Morphogenesis‐independent regulation of actin transcript levels in the pathogenic yeast Candida albicans

Delbrück¹,

Ernst²

1993

Molecular Microbiology

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The transcript level of the Candida albicans ACT1 gene (encoding actin) is strongly regulated during induction of hyphal morphogenesis. ACT1 mRNA declines rapidly during starvation pretreatment and quickly recovers in media inducing morphogenesis. The C. albicans URA3 and LEU2 mRNAs, as well as an ACT1 promoter/LAC4 fusion, are regulated similarly. The regulation of ACT1/LAC4 and unaltered mRNA stabilities suggest transcriptional regulation during morphogenesis. However, by individually testing morphogenesis induction parameters, it is shown that starvation and growth phase, but not hyphal formation, are responsible for ACT1 transcript regulation; this conclusion is confirmed by analyses of morphological mutants and by inhibition of hyphal development. Thus, the specific morphogenesis-induction conditions, but not morphogenesis per se, affect transcript levels in C. albicans.

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“…Nitrogen sources have also been shown to have an in£uence on the morphology of Mucor spp. [10] and Y. lipolytica [6]. However, at least in Y. lipolytica the results seem to contradict the foraging hypothesis since increasing concentrations of ammonium sulfate stimulated rather than inhibited formation of ¢laments [6].…”

Section: Introductionmentioning

confidence: 72%

Presence of organic sources of nitrogen is critical for filament formation and pH-dependent morphogenesis in Yarrowia lipolytica

Szabo

2002

FEMS Microbiology Letters

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Yeast dimorphism is an attractive model for the study of cell morphogenesis and differentiation. The non-conventional yeast Yarrowia lipolytica was chosen to characterise the regulation of dimorphic transition by extracellular pH and by the presence of organic sources of nitrogen. Organic nitrogen sources appear to be required for the morphogenic effect of pH. Two sets of mutants defective in either pHdependent or nitrogen source-dependent signalling pathway were analysed. The results suggest that the latter but not the former is required for both normal filament formation on solid medium and pH-dependent dimorphic behaviour of Y. lipolytica in liquid medium. We propose that in this organism pH affects the formation of hyphae indirectly by modulation of availability and/or utilisation of transportable sources of nitrogen. ß

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Mucor dimorphism.

Cited by 115 publications

References 184 publications

Comparative fatty acid profiling ofMucor rouxiiunder different stress conditions

Comparative fatty acid profiling ofMucor rouxiiunder different stress conditions

Morphogenesis‐independent regulation of actin transcript levels in the pathogenic yeast Candida albicans

Presence of organic sources of nitrogen is critical for filament formation and pH-dependent morphogenesis in Yarrowia lipolytica

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