Mucoid Degeneration of Wharton's Jelly. An Umbilical Cord Anomaly Threatening FŒTAL Life

Bergman, Per; Lundin, Per; Malmstrom, T

doi:10.3109/00016346109159935

Cited by 39 publications

(19 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Edema is apparent in the markedly swollen, glistening umbilical cord shown in Figure 238. It resembles the condition of "mucoid degeneration" described by Bergman et al (1961). These investigators believed that one of their patients died as a result of this degeneration.…”

Section: Cysts and Edemamentioning

confidence: 63%

Anatomy and Pathology of the Umbilical Cord and Major Fetal Vessels

Benirschke

Kaufmann

1995

Pathology of the Human Placenta

View full text Add to dashboard Cite

Section: Cysts and Edemamentioning

confidence: 63%

Anatomy and Pathology of the Umbilical Cord and Major Fetal Vessels

Benirschke

Kaufmann

1995

Pathology of the Human Placenta

View full text Add to dashboard Cite

“…Other possible physiopathologic mechanisms for this anomaly could be an incomplete fusion of the amniotic covering and the mesenchyme of the umbilical cord during early development, or a hypoplasia of this amniotic covering with a secondary loss of Wharton’s jelly 7. In 1961, Bergman, Lundin and Malmstrom12 described the first case in which a segment of the umbilical arteries were devoid of their Wharton’s jelly covering. The most common complication of this anomaly results in fetal demise, but cord constrictions have also been implicated in fetal growth restriction and fetal intolerance to labor;5 in the present case, fetal weight was adequate for gestation age.…”

Section: Discussionmentioning

confidence: 99%

Wharton s jelly absence: a possible cause of stillbirth

Damasceno¹,

Lima²

2013

ACR

View full text Add to dashboard Cite

The umbilical cord is a structure that provides vascular flow between the fetus and the placenta. It contains two arteries and one vein, which are surrounded and supported by gelatinous tissue known as Wharton’s jelly. There are many umbilical cord abnormalities that are related to the prognosis of fetus survival and birth weight. The authors report a case of umbilical cord constriction due to the localized absence of Wharton’s jelly, which was undiagnosed antenatally and had a fatal outcome. A review of the association between the absence of Wharton’s jelly and an unfavorable pregnancy outcome was undertaken.

show abstract

“…Its pathogenesis is not fully understood, but apparently it occurs after degeneration or loss of pre-existent Wharton's jelly, based on the notion that normal umbilical cord development is not possible in the absence of embryonal mesenchyme [2].…”

Section: Discussionmentioning

confidence: 99%

Splitting of the Umbilical Cord in a 13-Week-Old Fetus

Peres

2012

Pediatr Dev Pathol

View full text Add to dashboard Cite

There is an increasing interest in the physiology and pathology of the umbilical cord because it is recognized as an important source of placental and, consequently, fetal problems. During the postmortem examination of a severely macerated 13-week-old fetus, a split umbilical cord was noted. This rare finding was seen in the middle segment of the cord, the fetal and placental ends both being normal. The pathogenesis of this lesion is not fully understood, and it is possible that it results through focal degeneration of previously formed Wharton's jelly or secondary loss of Wharton's jelly due to incomplete fusion or hypoplasia of the amniotic covering. Whatever the pathogenesis, it is assumed that an umbilical vessel devoid of its protective Wharton's jelly is more prone to compression and thrombosis with all its deleterious effects. Death in this case was probably associated with the congenital heart defect also presented by the fetus. The rarity of this lesion is probably explained by the fact that it represents the end of the spectrum of longitudinal deficiency of Wharton's jelly, a relatively common finding.

show abstract

Mucoid Degeneration of Wharton's Jelly. An Umbilical Cord Anomaly Threatening FŒTAL Life

Cited by 39 publications

References 7 publications

Anatomy and Pathology of the Umbilical Cord and Major Fetal Vessels

Anatomy and Pathology of the Umbilical Cord and Major Fetal Vessels

Wharton s jelly absence: a possible cause of stillbirth

Splitting of the Umbilical Cord in a 13-Week-Old Fetus

Contact Info

Product

Resources

About