Mucoepidermoid Tumor of the Lacrimal Sac

Mucoepidermoid carcinoma of lacrimal sac

“…(15) Multiplanar CT imaging of the paranasal sinuses and orbit is essential for defining the extent of the tumor and for finding evidence of bony destruction of the lacrimal fossa (16).Magnetic resonance imaging is useful for distinguishing the lesion form adjacent retained secretions, hypertrophic inflammatory mucosa and adipose tissues (17) The treatment of LS tumors is often multidisciplinary and modalities can include surgery, chemotherapy, immunotherapy, and radiotherapy, depending of the histologic type and anatomic extent of the tumor (14) most patients underwent exenteration with postoperative radiation therapy when the soft tissue margins were positive for tumor infiltration. (11,12) The old age of our patient argued in favor of preoperative radiation to reduce the mass, followed by wide resection of the tumor…”

“…Ni et al (11) postulate that it may arise from either the LS wall serous gland epithelium or the columnar epithelium of the conjunctiva, with its globet cells. The first case of MEC arising in the LS was described in brazil in 1981 by Bambirra et al (12) An LS biopsy is the most important tool (13), biopsies are performed either to establish the diagnosis of a suspicious mass or to identify an abnormal lesion seen in the LS mucosa during DCR (14).The diagnosis of MEC typically requires the coexistence of 3 cell types:epidermoid,intermediate and mucin secreting cells. (15) Multiplanar CT imaging of the paranasal sinuses and orbit is essential for defining the extent of the tumor and for finding evidence of bony destruction of the lacrimal fossa (16).Magnetic resonance imaging is useful for distinguishing the lesion form adjacent retained secretions, hypertrophic inflammatory mucosa and adipose tissues (17) The treatment of LS tumors is often multidisciplinary and modalities can include surgery, chemotherapy, immunotherapy, and radiotherapy, depending of the histologic type and anatomic extent of the tumor (14) most patients underwent exenteration with postoperative radiation therapy when the soft tissue margins were positive for tumor infiltration.…”

Diagnosis and Management of Mucoepidermoid Carcinoma of the Lacrimal Duct

“…In fact, due to the gradual onset of symptoms and the coexisting rarity of these tumors, their diagnosis is delayed approximately half the time (Valenzuela et al, 2006b). A mucoepidermoid carcinoma is a subtype of a primary lacrimal sac tumor containing both mucous and epidermoid cells, of which 13 cases have been reported in the English literature (Bambirra et al, 1981;Bianchi et al, 2010;Fliss et al, 1993;Williams et al, 2003), and little has been reported on how to treat these tumors effectively (Bianchi et al, 2010).…”

“…In the past, for a mucoepidermoid carcinoma, complete orbital exenteration was frequently included in the therapeutic plan (Bambirra et al, 1981;Fliss et al, 1993). Recently, Parmar and his colleagues encountered a patient presenting with a low-grade mucoepidermoid carcinoma, and complete excision of the tumor with external beam radiotherapy was performed.…”

Surgical Treatment of Mucoepidermoid Carcinoma of the Lacrimal Sac

“…[1][2][3][4][5][6][7][8][9] Despite the fact that orbital exenteration has generally been recommended for these tumors, radical surgical resections with external radiation therapy might be effective.…”