Mucoepidermoid carcinoma of the lacrimal gland in a patient with the CRTC1-MAML2 fusion gene

Makino, Kensaku; Nakajima, Kei; Tsutsumi, Satoshi; Toriyama, Akane; Nonaka, Senshu; Okura, Hidehiro; Matsuzaka, Kenichi; Nagao, Toshitaka; Izumi, Hiroshi; Tomita, Shigeki; Ishii, Hisato

doi:10.1016/j.radcr.2021.08.075

Cited by 1 publication

(1 citation statement)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the group of 37 patients whose eye laterality was known, were 17 right eyes and 20 left eyes; there were no bilateral cases. The tumor’s cause is uncertain, possibly relating to ionizing radiation, gene translocation, malignant transformation of pleomorphic adenoma, HPV6 and HIV infection ( 2 , 5 – 8 ). This case is peculiar in that the presentation is in a middle-aged man who has metastasis to multiple organs including the contralateral eye.…”

Section: Discussionmentioning

confidence: 99%

Lacrimal gland mucoepidermoid carcinoma with contralateral eye and systemic metastasis: A rare case report and review of the literature

He²

2023

Front. Oncol.

View full text Add to dashboard Cite

Lacrimal gland mucoepidermoid carcinoma is very rare. It has a high risk of recurrence and metastasis, however, it rarely metastasizes to the contralateral eye in clinical practice. Here, we present a case of a 52-year-old man with lacrimal gland mucoepidermoid carcinoma who developed multiple recurrences and metastases of another eye and other sites throughout the body after receiving surgical intervention and regular radiotherapy, which will be of ophthalmic interest and unique. Clinical features, imaging findings, histopathology, treatments, and outcomes of this very rare case are provided. A literature review of previously published cases of this disease is performed, with an emphasis on the latest diagnosis and treatment. The prognosis of tumor recurrence and metastasis is poorer, surgery with a negative margin in conjunction with adjuvant therapies is crucial for preventing local recurrence and distant metastasis and enhancing the survival rate.

show abstract

Section: Discussionmentioning

confidence: 99%

Lacrimal gland mucoepidermoid carcinoma with contralateral eye and systemic metastasis: A rare case report and review of the literature

He²

2023

Front. Oncol.

View full text Add to dashboard Cite

show abstract

Mucoepidermoid carcinoma of the lacrimal gland in a patient with the CRTC1-MAML2 fusion gene

Cited by 1 publication

References 15 publications

Lacrimal gland mucoepidermoid carcinoma with contralateral eye and systemic metastasis: A rare case report and review of the literature

Lacrimal gland mucoepidermoid carcinoma with contralateral eye and systemic metastasis: A rare case report and review of the literature

Contact Info

Product

Resources

About