Muciparous Epidermal Tumor

Kwittken, J

doi:10.1001/archderm.1974.01630040060016

Cited by 13 publications

(5 citation statements)

References 2 publications

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“…In support of this concept, Misago et al recently noted expression of CK19, a marker of stem cells, in a case of BD with trichilemmal differentiation . A report of mucinous differentiation in a benign epidermal lesion, predating reports of BD with adnexal differentiation, is also of interest in this regard . Our own hypothesis is that modified and particularly malignant epidermal keratinocytes can exhibit stem‐cell‐type characteristics.…”

Section: Discussionmentioning

confidence: 73%

Bowen disease with invasive mucin‐secreting sweat gland differentiation: Report of a case and review of the literature

et al. 2019

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Bowen disease (BD) with divergent adnexal differentiation is a rare composite cutaneous tumor featuring different phenotypic elements. Sebaceous, poroid and trichilemmal invasive components have been described in this setting and very infrequent reports of mucinous glandular differentiation are extant. Clinically, these tumors are not sufficiently distinctive to enable recognition without histopathological evaluation. From a microscopic perspective, care must be taken to exclude a collision tumor as well as other combined cutaneous neoplasms featuring squamous and glandular differentiation. Direct continuity between the two epithelial phenotypes helps to establish the correct diagnosis and generates interesting speculation about the pathogenesis of these and other epithelial skin tumors. We describe a case of BD in continuity with an invasive adenocarcinoma exhibiting mucinous sweat gland differentiation on the face of an elderly man. Details of the case are outlined with the objective of adding to a scant literature on this topic.

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Section: Discussionmentioning

confidence: 73%

Bowen disease with invasive mucin‐secreting sweat gland differentiation: Report of a case and review of the literature

et al. 2019

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“…In 1974, Kwittken made the first description of this tumor as a “muciparous epidermal tumor,” 3 although, according to Trotter et al 1 , there is a previous report of a similar lesion in the German literature. The term mucinous syringometaplasia was coined in 1979 by King and Barr 4 when they described a solitary skin lesion, which drained serous fluid, in the left heel of a 23-year-old patient.…”

Section: Discussionmentioning

confidence: 99%

Mucinous Syringometaplasia: Case Report and Review of the Literature

Macías-Alonso¹,

Solís-Ledesma

Sánchez-Tadeo³

et al. 2022

The American Journal of Dermatopathology

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Mucinous syringometaplasia is a rare and poorly recognized entity that usually presents as a warty tumor in acral regions. It is more frequent in men, and the age of presentation is variable. Typically, it has been reported as a solitary lesion with a warty appearance that occasionally can drain serous material. The affected sites include head, neck, breast, acral regions, and buttocks. The evolution over time is variable. The pathogenesis has not been elucidated. Diagnosis is established through histopathology, the characteristic feature is an epidermal invagination, which creates a structure similar to a "pore" at the dermal level. The clinical differential diagnosis is mainly with a viral wart, but it can also resemble basal cell carcinomas and other adnexal tumors. The treatment is surgical, and no recurrences have been reported to date. We describe the case of a 25-year-old woman who presented with a lesion on one of her eyelids. A shave removal of the lesion was performed, and the diagnosis was established by histopathologic examination.

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“…MS was first described in 1931 on the palm of the hand in the German literature 29 . Over four decades later, it was first reported by Kwitten 30 in the English literature as muciparous epidermal tumor and is most often regarded as a metaplastic change in pre‐existing sweat ducts and thought to be the result of pressure or trauma. Clinically, they appear as verruca‐like or basal cell carcinoma‐like lesions occurring mostly on acral skin.…”

Section: Discussionmentioning

confidence: 99%

Mucinous hidradenoma: a report of three cases

Goh

Carr²,

Dayrit

et al. 2007

J Cutan Pathol

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Mucinous cutaneous adnexal tumors are an uncommon occurrence. We describe three cases of mucinous hidradenoma characterized by diffuse and prominent mucinous cell proliferation and discuss the relevant literature. The patients (two men and one woman) ranged in age from 32 to 72 years. The lesions were completely excised, and all patients were alive without evidence of disease (follow-up interval 3-4 years). Case 1 presented as a 1.3-cm eyelid nodule and histology showed a mucinous apocrine hidradenoma with a proliferation of mucinous cells and apocrine glands. Case 2, from the shoulder of a 40-year-old man, was a 2.5-cm well-circumscribed nodule composed of hyperplastic villoglandular proliferation of mucinous cells with focal squamous whorls and focal columnar glandular cells showing decapitation secretion. The tumor was also interpretated as a mucinous hidradenoma, most likely of follicular-apocrine origin. Case 3 was a 3.0-cm scalp nodule. The histology showed a mucinous clear-cell hidradenoma composed of numerous mucinous glands amidst small squamous cells with clear cytoplasm and a hyalinized fibrovascular stroma.

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Muciparous Epidermal Tumor

Cited by 13 publications

References 2 publications

Bowen disease with invasive mucin‐secreting sweat gland differentiation: Report of a case and review of the literature

Bowen disease with invasive mucin‐secreting sweat gland differentiation: Report of a case and review of the literature

Mucinous Syringometaplasia: Case Report and Review of the Literature

Mucinous hidradenoma: a report of three cases

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