Mucinous eccrine naevus

Yoshizawa, Junko; Hozumi, Yasukazu; Katagiri, Yoshiyuki; Kawaguchi, Masakazu; Shimanuki, Miwa; Suzuki, Tamio

doi:10.1111/j.1468-3083.2008.02854.x

Cited by 7 publications

(9 citation statements)

References 5 publications

(12 reference statements)

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“…Vessels in the lesion close to the glands are thicker than in normal glands . Mild fibroblastic hyperplasia can present in the dermis . Alcian blue staining performed at pH 2.5 is strongly positive, showing abundant mucinous deposition in the stroma surrounding the eccrine gland in the dermis.…”

Section: Histopathological Findings and Differential Diagnosismentioning

confidence: 98%

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Mucinous eccrine naevus: case report and review of the literature

Tempark

Shwayder

2012

Clinical and Experimental Dermatology

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SummaryMucinous eccrine naevus (MEN) is an extremely rare variant of eccrine naevus. There are only nine reported cases in the English literature. We report a 3-monthold boy with a congenital lesion on the lower back, and review the other cases in the literature. In most cases, MEN presents before puberty. The commonest presentation is a unilateral, solitary, brownish nodule without hyperhidrosis occurring on the legs. The diagnosis of this condition is confirmed by the characteristic histopathological features. Treatment options may be considered if symptomatic.

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Section: Histopathological Findings and Differential Diagnosismentioning

confidence: 98%

“…Plastic surgery was carried out for a case of a tender and hypertrophic lesion of the toe (patient 5) . Monthly injections of intralesional corticosteroid monthly were reported to flatten the lesion on the inner thigh (patient 7), whereas topical corticosteroid possibly relieved tenderness in another lesion (patient 6) …”

Section: Treatmentmentioning

confidence: 99%

Mucinous eccrine naevus: case report and review of the literature

Tempark

Shwayder

2012

Clinical and Experimental Dermatology

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“…A role for mechanical stress and trauma has been suggested, or for some cytokines such as growth factors that stimulate the fibroblasts to synthesize more mucin. 50,51 Management and prognosis MEN does not regress spontaneously. Surgical excision should be considered in case of tenderness, swelling and/or hyperhidrosis, otherwise a wait-and-see approach is suggested.…”

Section: Pathogenesismentioning

confidence: 99%

Primary paediatric cutaneous mucinoses

Rongioletti

2019

Br J Dermatol

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Summary Background Primary cutaneous mucinoses are a heterogeneous group of diseases characterized by the abnormal deposition of glycosaminoglycans (mucin) in the skin. This is the main histopathological clue resulting in distinctive clinical presentations. They are usually diseases of adult age and are uncommon in children, in whom diagnosis and management are difficult tasks. In particular, the classification of primary cutaneous mucinoses occurring in childhood is a difficult and confusing challenge because of the very limited number of described cases and overlaps in their clinicopathological features in the absence of reports of homogeneous case series. Objectives The aim of this review is to help dermatologists and paediatricians to identify patients with cutaneous mucinoses at a paediatric age and to enable institution of appropriate management. A classification of primary paediatric cutaneous mucinoses is also proposed. Results New investigations have yielded significant insights into a classification of paediatric cutaneous mucinoses. Conclusions The current update tries to offer a more meaningful guide to the diagnosis and treatment of these rare diseases in paediatric patients. What's already known about this topic? The nosography of primary cutaneous mucinoses occurring in childhood is confusing because of the very limited number of cases and overlaps in their clinicopathological features in the absence of homogeneous case series. The diagnosis and management of paediatric patients with cutaneous mucinoses are also difficult as these diseases are rarely seen in children. What does this study add? New investigations have yielded significant insights into a classification of paediatric cutaneous mucinoses. The current update tries to offer a more meaningful guide to diagnosis and treatment of these rare diseases in patients of paediatric age.

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“…Intralesional botulinum toxin and triamcinolone acetonide injections have also been reported. 1,7 MEN varies in clinical presentation but is specific in histopathological presentations, and thus histopathological examination is required for definitive diagnosis. The case (H&E stain, 340).…”

Section: Discussionmentioning

confidence: 99%

“…2,3 To our knowledge, only 7 cases have been reported in the literature up to now. [2][3][4][5][6][7][8] We report herein a case of MEN not specific in clinical presentations but typical in histopathological manifestations.…”

mentioning

confidence: 93%