Mucinous cystadenoma mimicking simple renal parenchymal cyst in a horseshoe kidney

Abstract

We report a case of mucinous cystadenoma in a horseshoe kidney which radiologically resembled a simple renal cyst. In the published literature, three cases of mucinous cystadenoma of renal origin have been reported. Although these tumors are believed to originate from the renal pelvis, the cyst in the present case originated from renal parenchyma. The significance of this particular case is the radiological features, which mimick a simple renal parenchymal cyst and contribute to the histopathological definition of an extremely rare disease.

Mucinous cystadenoma of a horseshoe kidney: A case report and literature review

“…None of the previous reports correctly diagnosed the disease before surgery; the final diagnosis was made only after tumour excision. The density of simple renal cysts ranges from −10 to +20 HU on CT. 2 With our patient, the density of the cystadenoma ranged from 10 to 20 HU and the radiologic features mimicked a renal parenchymal cyst. 2 Mucinous cystadenoma of the kidney may therefore be underdiagnosed by routine imaging studies.…”

“…Among these 13 cases, included the present case, 8 (61.5%) occurred in men and 5 in women. [1][2][3][4][5][6][7][8][9] The median age was 59 (range: 27-79). The median size of the cystic tumour was 156 mm (range: 35-370).…”

“…The median size of the cystic tumour was 156 mm (range: 35-370). [1][2][3][4][5][6][7][8][9] Despite their large size, 6 tumours (46.1%) were asymptomatic and detected incidentally by ultrasonography and/or CT.…”

“…[1][2][3][4][5][6][7][8][9] Some authors have postulated that the development of mucinous cystadenoma with an intestinal phenotype in the kidney involves urolithiasis, infections, or both, and these events may induce intestinal metaplasia. 6 In fact, urolithiasis was reported in 7 cases.…”

Well-Differentiated Mucinous Cystadenocarcinoma of the Renal Pelvis

“…Kobayashi et al have related the histogenesis adenocarcinoma to metaplasia of transitional cell carcinoma (7). There have been cases as mucinous cystadenoma of the renal pelvis with malignant transformation (2) as in our case, a mucin-producing cystadenoma, borderline malignancy of the renal pelvis and ureter (1), mucinous cystadenoma in a horseshoe kidney (12,13), intestinal type of villous adenoma (14) and mucinous adenocarcinoma of renal pelvis and villous adenoma of bladder after caecal augmentation of bladder (15).…”