Mucinous carcinoma of the breast: iconographic essay with histopathological correlation

Coeli, Gustavo Nunes Medina; Reis, Henrique Ferreira dos; Bertinetti, Dayse Ribeiro; Faria, Francesca Maia; Tiezzi, Daniel Guimarães; Oliveira, Tatiane

doi:10.1590/s0100-39842013000400011

Cited by 2 publications

(4 citation statements)

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“…At US it presents as a hypoechogenic image with non-circumscribed margins, and in 2% of cases it may be hyperechogenic. Probably, the hyperechogenicity is due to reflective interfaces caused by growth and infiltration of the cellular component, and fatty inclusions involving a poorly perceptible hypoechogenic, hyalinized center ( Figure 12 ) ( 4 , 14 ) .…”

Section: Malignant Lesionsmentioning

confidence: 99%

Hyperechoic breast lesions: anatomopathological correlation and differential sonographic diagnosis

et al. 2016

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Hyperechoic lesions are not a frequent finding at breasts ultrasonography, and most of times are associated with benign pathologies that do not require further evaluation. However, some neoplasms such as invasive breast carcinomas and metastases may present with hyperechogenicity. Thus, the knowledge about differential diagnoses and identification of signs of lesion aggressiveness are of great relevance to avoid unnecessary procedures or underdiagnosis, and to support the correct clinical/surgical approach. On the basis of such concepts, the present essay describes and illustrates the main features of hyperechoic lesions at breast ultrasonography in different cases, with anatomopathological correlation.

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Section: Malignant Lesionsmentioning

confidence: 99%

Hyperechoic breast lesions: anatomopathological correlation and differential sonographic diagnosis

et al. 2016

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“…7 Medulloblastoma is a malignant and invasive cerebellar neoplasm that manifests in children and young adults with dissemination through the cerebrospinal fluid. 8,9 Among adults, 80% occur between 21 and 40 years of age. According to the World Health Organization (Louis et al, 2007), 10 medulloblastomas are classified histologically into 5 types: desmoplastic/nodular (pale islands, highly proliferative cells, nodules with reduced cellularity), extensive nodular, classic, large cell, and anaplastic.…”

Section: Introductionmentioning

confidence: 99%

“…The higher the amount of mucin the better the prognosis. 9 Após 13 meses, a paciente foi diagnosticada com carcinoma mucinoso de mama, sendo submetida a mastectomia, quimioterapia adjuvante e atualmente está sendo tratada com endocrinoterapia. Concluímos, com base na característica metacrônica da neoplasia e características clínicas, que a paciente apresenta a síndrome de Li-Fraumeni, doença autossômica dominante com mutação do gene TP53, que é o principal gene envolvido nesta síndrome.…”

Section: Introductionunclassified

“…The National Cancer Institute estimates that 59,700 new cases of breast cancer will be expected in 2018, corresponding to 29% of female cancers, in Brazil. 16 Mucinous cancer, also known as colloid carcinoma of the breast, is considered an atypical subtype of invasive carcinoma; it affects more frequently women of advanced age and represents 1 to 7% of the total of mammary neoplasias 9 . Mucins are complex carbohydrates released by connective tissue cells and mainly by specialized epithelial cells.…”

Section: Introductionmentioning

confidence: 99%

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Metachronic Breast and Cerebellar Neoplasm in a Young Patient

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et al. 2020

Rev Bras Ginecol Obstet

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Several factors trigger the development of genetic mutations that are responsible for causing a neoplasm. Medulloblastoma is a malignant and invasive cerebellar neoplasm, that affects children and young adults. Mucinous carcinoma is a special type of breast cancer. Being a special atypical subtype of invasive carcinoma, it most frequently affects women of advanced age and represents 1 to 7% of all breast cancers. The reported case aims to show the rarity of the occurrence of desmoplastic medulloblastoma and mammary mucinous carcinoma in a young patient in a short period of time, in different sites, without direct anatomical attachment and without occurrence of metastasis. Initially, this patient had a desmoplastic medulloblastoma and was treated with lumpectomy and radiotherapy. After 13 months, the patient was diagnosed with a mucinous breast carcinoma, underwent mastectomy, adjuvant chemotherapy and is currently undergoing endocrinotherapy. We conclude, based on the metachronous characteristic of the neoplasia and clinical characteristics, that the patient is likely to have Li-Fraumeni syndrome, an autosomal dominant disease with mutation of the TP53 gene, which is the the main involved. Because the patient does not present all the characteristics of the phenotype of the syndrome, she can thus be classified as having Li-Fraumeni variant or Li-Fraumeni-like syndrome.

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Mucinous carcinoma of the breast: iconographic essay with histopathological correlation

Cited by 2 publications

References 20 publications

Hyperechoic breast lesions: anatomopathological correlation and differential sonographic diagnosis

Hyperechoic breast lesions: anatomopathological correlation and differential sonographic diagnosis

Metachronic Breast and Cerebellar Neoplasm in a Young Patient

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