Mucinous Appendiceal Neoplasms: Preoperative MR Staging and Classification Compared with Surgical and Histopathologic Findings

Low, Russell N.; Barone, Robert M.; Gurney, Jonathan M.; Müller, W

doi:10.2214/ajr.07.2018

Cited by 55 publications

(30 citation statements)

References 32 publications

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“…Our results concur with the description provided by Outwater et al [9] in which mucinous adenocarcinomas presented with high signal intensity on T2-weighted images. This characteristic, described in other mucinous tumors seen elsewhere in the body [14, 15], seems to render prostate mucinous adenocarcinomas occult against the high T2 signal intensity of the normal peripheral zone background. However, to our knowledge, this is the first description of the MR spectroscopy findings seen in this subtype of prostate cancer.…”

Section: Discussionmentioning

confidence: 88%

Mucinous Adenocarcinoma of the Prostate: MRI and MR Spectroscopy Features

Westphalen

Coakley

Kurhanewicz

et al. 2009

American Journal of Roentgenology

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Section: Discussionmentioning

confidence: 88%

Mucinous Adenocarcinoma of the Prostate: MRI and MR Spectroscopy Features

Westphalen

Coakley

Kurhanewicz

et al. 2009

American Journal of Roentgenology

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“…According to a preliminary report, the use of MRI seems promising in disease staging and patient selection for cytoreductive surgery [34]. PET is of very limited value for low-grade mucinous lesions, such as pseudomyxoma [35].…”

Section: Preoperative Evaluationmentioning

confidence: 99%

Consensus statement on the loco‐regional treatment of appendiceal mucinous neoplasms with peritoneal dissemination (pseudomyxoma peritonei)

Moran

Baratti²,

Yan

et al. 2008

Journal of Surgical Oncology

206

107

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Pseudomyxoma peritonei (PMP) is a rare condition mostly originating from low malignant potential mucinous tumours of the appendix. Although this disease process is minimally invasive and rarely causes haematogenous or lymphatic metastases, expectation of long-term survival are limited with no prospect of cure. Recently, the combined approach of cytoreductive surgery (CRS) and perioperative loco-regional chemotherapy (PLC) has been proposed as the standard of treatment for the disease. The present paper summarizes the available literature data and the main features of the comprehensive loco-regional treatment of PMP. The controversial issues concerning the indications and technical methodology in PMP management were discussed through a web-based voting system by internationally known experts. Results were presented for further evaluation during a dedicated session of "The Fifth International Workshop on Peritoneal Surface Malignancy (Milan, Italy, December 4-6, 2006)". The experts agreed that multiple prospective trials support a benefit of the procedure in terms of improved survival, as compared with historical controls. Concerning the main controversial methodological questions, there was an high grade of consistency among the experts and agreement with the findings of the literature.

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“…The primary goal of preoperative imaging is to select patients suitable for the intended surgical procedure [ 21–24 ] , and the secondary target is the prediction of the clinical outcome after therapy [ 25 ] . In regard of PC this means to determine in which patients complete cytoreduction could be achieved by means of peritonectomy and HIPEC, and what could be expected regarding relapse of PC and survival time after peritonectomy [ 26–28 ] .…”

Section: Discussionmentioning

confidence: 99%

Correlation of preoperative magnetic resonance imaging of peritoneal carcinomatosis and clinical outcome after peritonectomy and HIPEC after 3 years of follow-up: preliminary results

et al. 2013

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Purpose: In patients with peritoneal carcinomatosis, cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is an evolving approach with curative intention. Previous studies indicate a correlation between preoperative magnetic resonance imaging (MRI) and surgical findings regarding the extent of peritoneal carcinomatosis. The aim of this study was to assess retrospectively whether preoperative MRI can predict the outcome and is therefore a suitable tool for patient selection. Materials and methods: Fifteen patients with laparoscopically proven peritoneal carcinomatosis were preoperatively examined using a 1.5-T whole-body MRI system. Results were correlated with surgical exploration. Follow-up was done by contrast-enhanced abdominal computed tomography and, if suspicious for recurring disease, laparoscopy or laparotomy. Survival time and interval to recurring disease were correlated with the preoperative peritoneal carcinomatosis index (PCI) on MRI (Spearman’s rank correlation). Results: In five patients radical resection could not be achieved (PCI 34 ± 6.9); survival time was 78.2 ± 54.1 days. In seven patients recurring disease was found 430 ± 261.2 days after initial complete cytoreduction (PCI 11.6 ± 6.9); survival time was 765.9 ± 355 days. Two patients are still alive after 3 years. Two patients with initially complete cytoreduction are without recurring disease after 3 years (PCI 5 and 12). One patient was lost for follow-up. Conclusions: Results of the preoperative MRI correlate well with the surgical PCI, postoperative resection status, and survival time. MRI might be a suitable technique for patient selection when considering peritonectomy and HIPEC. In our patients the outcome seems to correlate well with the extent of peritoneal carcinomatosis found by the preoperative MRI.

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Mucinous Appendiceal Neoplasms: Preoperative MR Staging and Classification Compared with Surgical and Histopathologic Findings

Abstract: Of the MR techniques evaluated, delayed gadolinium-enhanced MRI was the most accurate for the staging and classification of mucinous appendiceal neoplasms and provided prognostic information useful for patient selection.

Cited by 55 publications

References 32 publications

Mucinous Adenocarcinoma of the Prostate: MRI and MR Spectroscopy Features

Mucinous Adenocarcinoma of the Prostate: MRI and MR Spectroscopy Features

Consensus statement on the loco‐regional treatment of appendiceal mucinous neoplasms with peritoneal dissemination (pseudomyxoma peritonei)

Correlation of preoperative magnetic resonance imaging of peritoneal carcinomatosis and clinical outcome after peritonectomy and HIPEC after 3 years of follow-up: preliminary results

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