Mucinous (Adenocystic) Carcinoma of the Skin

Mucinous Eccrine Adenocarcinoma of the Periocular Region

“…Most reports suggest that MEA of the skin primarily affects people in their fifth to seventh decades of life (mean age at diagnosis, 63 years), but MEA has been found in patients as young as 8 years and as old as 91 years. 4,37 Of the reported cases, 62% have occurred in men and 38% in women.…”

A rare case of fatal primary cutaneous mucinous carcinoma of the scalp with multiple in-transit and pulmonary metastases

“…However, with traditional surgical excision, local tumor recurrence is very common; up to 30% to 40%. 3,4 Several recent reports have successfully utilized Mohs micrographic surgery to treat cutaneous mucinous carcinomas. [12][13][14] Mohs micrographic surgery appears to be a suitable and effective means of treatment since these tumors usually form contiguous masses.…”

“…Only two cases of systemic metastases resulting from a primary cutaneous mucinous carcinoma have been previously reported. 1,3 In addition, one case of fatality caused by local extension of the disease has also been reported. 3 However, in our patient, the tumor was extremely aggressive with development not only of multiple local tumors, but also of local metastases to the parotid gland and cervical lymph nodes, as well as eventual systemic metastases to the lungs.…”

“…Accordingly, death from this tumor is rare and it usually has a favorable prognosis. 1,3,5 Cutaneous mucinous carcinomas originate from sweat glands; however, it is controversial whether the cells are of eccrine or apocrine derivation. 1,4,6 Histologically, there are light-and dark-staining epithelial cells that form cords, nests, and ducts that are embedded in clear amorphous areas of sialomucin separated by thin fibrous septae.…”

Mucinous adenocarcinoma of the face

“…Mucinous adenocarcinomas can arise in the stomach, lower gastrointestinal tract, breast, salivary glands or lachrymal glands 6 . Distinction between primary cutaneous tumours and mucinous adenocarcinomas metastatic to the skin can be…”