2023
DOI: 10.3389/fmed.2023.1209439
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mTOR signaling in hair follicle and hair diseases: recent progress

Wei Tu,
Yu-Wei Cao,
Mang Sun
et al.

Abstract: Mammalian target of rapamycin (mTOR) signaling pathway is a major regulator of cell proliferation and metabolism, playing significant roles in proliferation, apoptosis, inflammation, and illness. More and more evidences showed that the mTOR signaling pathway affects hair follicle circulation and maintains the stability of hair follicle stem cells. mTOR signaling may be a critical cog in Vitamin D receptor (VDR) deficiency-mediated hair follicle damage and degeneration and related alopecia disorders. This revie… Show more

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