MtDNA control region and RFLP data for Sicily and France

Abstract

The forensic application of mtDNA typing requires large databases which are regionally well defined. To further this aim, we have typed mtDNA in a sample of 111 French and 106 Sicilians. The French were typed for both hypervariable segments (HVR1 and HVR2) of the mtDNA control region, whereas the Sicilians were only typed for HVR1, but in addition for the coding region RFLP markers for mtDNA groups H, I, J, K, L, M, T, U, V and X. In both samples, the predominant sequence type by far was the Cambridge reference sequence. Comparing HVR1 sequences, we found that the French sample was twice as diverse as the Sicilian sample as measured by sequence matches. A further set of sequence match comparisons including the French, Sicilian, and the published British mtDNA samples, demonstrate that sequence matching probabilities within samples differ by less than a factor of 2 from the matching probabilities between samples.

Mitochondrial DNA Portrait of Latvians: Towards the Understanding of the Genetic Structure of Baltic‐Speaking Populations

“…Population data are from: LAT -Latvians, this study; LIT -Lithuanians, (Kasperavičiūtė et al 2004); RUS -Russians, (Malyarchuk & Derenko, 2001;Malyarchuk et al 2002;Orekhov et al 1999); POL -Poles, (Malyarchuk et al 2002;Richards et al 2000); GER -Germans, (Baasner et al 1998;Hofmann et al 1997;Lutz et al 1998;Pfeiffer et al 1999;Richards et al 1996); FRA -French, (Cali et al 2001;Danan et al 1999;Dubut et al 2004); NORNorwegians, (Helgason et al 2001;Opdal et al 1998;Passarino et al 2002); FIN -Finns, (Kittles et al 1999;Lahermo et al 1996;Meinilä et al 2001;Pult et al 1994;Sajantila et al 1995) Loogväli et al (2004), …”

“…Committee of Riga Stradins University approved the research protocol. For comparison, the mtDNA database of 11,236 individuals, consisting of published mtDNA data (Baasner et al 1998;Bermisheva et al 2002;Cali et al 2001;Comas et al 1998;Crespillo et al 2000;Derbeneva et al 2002aDerbeneva et al , 2002bDerenko et al 2003;Dimo-Simonin et al 2000;Dubut et al 2004;Helgason et al 2001Helgason et al , 2000Kasperavičiūtė et al 2004;Kittles et al 1999;Lahermo et al 1996;Larruga et al 2001;Loogväli et al 2004;Lutz et al 1998;Malyarchuk & Derenko, 2001;Malyarchuk et al 2003Malyarchuk et al , 2002Meinilä et al 2001;Mogentale-Profizi et al 2001;Passarino et al 2002;Pereira et al 2001;Pfeiffer et al 1999;Richards et al 2000;Tagliabracci et al 2001) as well as our unpublished mtDNA data from 4732 individuals from different Eurasian populations, were used as background information for the analysis.…”

Islands Inside an Island: Reproductive Isolates on Jerba Island

“…2.0 (Schneider et al, 2000). Pairwise haplotype matchings within (mw) and between (mb) samples were calculated as described in Brinkmann et al (1999) and Cali et al (2001).…”

A Reassessment of Genetic Diversity in Icelanders: Strong Evidence from Multiple Loci for Relative Homogeneity Caused by Genetic Drift

“…A set of 7245 HVS1 sequences was analysed between sites 16090-16365 (276 base-pairs). In addition to sequences analysed in Helgason et al (2000aHelgason et al ( , 2001, the following are added: 50 Germans (Baasner et al 1998), 106 Sicilians (Cali et al 2001), 118 Spanish (Crespillo et al 2001), 154 Swiss (DimoSimonin et al 2000, 300 Yugoslavian (see Table 2), 20 Finns and 10 Polish (Jorde et al 2000), 50 Russians, (Malyarchuk & Derenko, 2001), 436 Poles and 201 Russians (Malyarchuk et al 2002), 129 Slovakians (E. Metspalu, T. Kivisild, K. Kaldma, M. Reidla & R. Villems, GenBank accession numbers AJ240164-AJ240292), 74 Norwegians (Passarino et al 2002), 241 Portuguese (Pereira et al 2000), 300 Canary Islanders (Rando et al 1999), 83 Italians (Tagliabracci et al 2001) and 186 Cretans (R. Villems, GenBank accession numbers AJ274757-AJ274942). Sequences that did not completely span the regions defined above were omitted from analysis, and population samples analysed in Helgason et al (2000a) with sample sizes below 70 were excluded.…”