MTA versus Biodentine: Review of Literature with a Comparative Analysis

Kaur, Mandeep; Singh, Harpreet; Dhillon, Jaidev Singh; Batra, Munish; Saini, Meenu

doi:10.7860/jcdr/2017/25840.10374

Cited by 166 publications

(206 citation statements)

References 56 publications

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“…That is attributed to a notable increase in alkaline phosphatase expression and calcium nodule formation compared to the MTA characteristics [70]. The antibacterial properties of BD and MTA can refer to the high alkaline pH of these materials, which has an inhibitory effect on the growth of microorganism and causes disinfection of dentin (Table 3) [115].…”

Section: Biodentinementioning

confidence: 99%

Bio-Inductive Materials in Direct and Indirect Pulp Capping—A Review Article

2020

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The article is aimed at analyzing the available research and comparing the properties of bio-inductive materials in direct and indirect pulp capping procedures. The properties and clinical performances of four calcium-silicate cements (ProRoot MTA, MTA Angelus, RetroMTA, Biodentine), a light-cured calcium silicate-based material (TheraCal LC) and an enhanced resin-modified glass-ionomer (ACTIVA BioACTIVE) are widely discussed. A correlation of in vitro and in vivo data revealed that, currently, the most validated material for pulp capping procedures is still MTA. Despite Biodentine's superiority in relatively easier manipulation, competitive pricing and predictable clinical outcome, more long-term clinical studies on Biodentine as a pulp capping agent are needed. According to available research, there is also insufficient evidence to support the use of TheraCal LC or ACTIVA BioACTIVE BASE/LINER in vital pulp therapy.

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Section: Biodentinementioning

confidence: 99%

Bio-Inductive Materials in Direct and Indirect Pulp Capping—A Review Article

2020

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“…The efficacy of the biological treatment of the pulp is higher in the younger patients as compared to the older patients [8]. This material is also used for sealing root perforation [9,10]. The teeth with perforations treated with Biodentine TM show regression of the inflammatory process and reduction in the bone resorption over time [1].…”

Section: Introductionmentioning

confidence: 99%

Analysis of the Activity and Expression of Cyclooxygenases COX1 and COX2 in THP-1 Monocytes and Macrophages Cultured with BiodentineTM Silicate Cement

Barczak

Palczewska-Komsa

Nowicka

et al. 2020

IJMS

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BiodentineTM is a material based on hydrated calcium silicate with odontotropic properties. However, from the clinician’s perspective, every material used to fill a tooth—even those showing the optimal biochemical parameters—is in fact a foreign body introduced to the organism of the host. Therefore, apart from the chemical parameters of such materials, equally important is the so-called biocompatibility of such materials. The aim of the study was to investigate whether BiodentineTM, used in the regeneration of the pulp-dentine complex, may affect the expression of the enzymes cyclooxygenase 1 (COX1) and cyclooxygenase 2 (COX2) in THP-1 monocytes/macrophages and the amount of prostanoids synthesized by these enzymes-precursors of biologically active prostanoids such as prostaglandin E2 (PGE2) and thromboxane (TXB2) which are mediators of inflammation. An original aspect of this research is the use of the THP-1 monocyte/macrophage cell model and the use of biomaterial in direct contact with cells. In this way we tried to reflect the clinical conditions of regenerative pulp and periodontal tissue treatment using BiodentineTM. The results of our study showed a lack of macrophage activation (measured by flow cytometry) and a lack of stimulation of the expression of the studied cyclooxygenase enzymes (measured by Western blotting and fluorescent microscopy), as well as a lack of increase in the concentration (measured by ELISA method) of their inflammatory mediators (PGE2 and TXB2) in vitro incubated with BiodentineTM.

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“…It was used effectively for root end filling, pulp capping, apexification and root perforation repair 18,19 . Nonetheless, MTA experiences some weaknesses including extended setting time (around two hours), washouts, staining of coronal dentine and impaired mechanical properties 2,17,20,21 . Bismuth oxide is claimed as responsible for most of these downsides 22,23,24 .…”

Section: Introductionmentioning

confidence: 99%

“…It contains calcium silicate, calcium carbonate, zirconium oxide instead of bismuth oxide added to improve material's radiopacity and calcium chloride added in liquid component to reduce its setting time 13,14 . Biodentine is considered as superior to MTA due to higher biocompatibility of zirconium oxide in comparison to bismuth oxide and zirconium ability to increase material's toughness 16,21,29 . Zirconium oxide is well known in dentistry as a part of different forms of zirconia ceramics 17 .…”

Section: Introductionmentioning

confidence: 99%

The advantages and disadvantages of biodentine: Satisfactory mechanical properties and radiopacity not meeting ISO standard

Milutinović-Smiljanić

Ilic

Danilović

et al. 2021

VOJNOSANIT PREGL

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Background/ Aim. The aim of this study was to characterize the physicochemical properties of the commercially available calcium silicate based dental cement Biodentine (Septodont). Methods. Material elucidation included measurements of radiopacity, scanning electron microscopic and x-ray dispersive analyses, wettability, Fourier transform infrared spectroscopy, microindentation, micro-to nano-porosity, setting time, pH and calcium ion release. Cells were grown on Biodentine surface in order to evaluate its behaviour under biological conditions. Results. The radiopacity of the cement (2.8 mmAl) was below ISO requirement for a root canal filling material. The cement was composed of fine powder with particles similar in size and shape changing from oval to cubic after soaking in simulated body fluid. Calcium silicates and calcium carbonate are the main compounds of the cement. Biodentine demonstrated good micromechanical properties and low porosity attributed to micro porosity with average pores size of 92 μm. Wettability (contact angle=41°), calcium ions release (0.098 μg/cm²) and pH of storage solution (9.07) showed satisfactory characteristics. Cells presented intimate contact with cement particles indicating its good biocompatibility. Conclusion. Biodentine exhibits good mechanical and physicochemical characteristics, but possesses insufficient radiopacity. Keywords: Biodentine; calcium silicate; dental cement; reference point indentation; micro computed tomography. Apstrakt Uvod/Cilj. Cilj ove studije bio je karakterizacija fiziĉkohemijskih osobina komercijalno dostupnog dentalnog cementa na bazi kalcijum silikata, Biodentina (Septodont). Metode. Ispitivanje materijala ukljuĉivalo je merenja radiografskog kontrasta, skening elektronsku mikroskopiju i radiografsku disperzivnu analizu, kvašenje, Furieovu transformocionu infracrvenu spektroskopiju, ĉvrstine, mikroi nano-poroznosti, vremena vezivanja, pH vrednosti i oslobaĊanja kalcijumovih jona. Ćelije su uzgajane na površini Biodentina sa ciljem da se ispita njegovo ponašanje u biološkim uslovima. Rezultati. Radiološki kontrast 4 cementa (2.8 mm Al) bio je niži od ISO standarda za materijale namenjene punjenju kanala korena. Cement se sastojao od finog praha sa ĉesticama male veliĉine i oblika koji se iz ovalnog menjao u kockasti nakon potapanja u simuliranu telesnu teĉnost. Glavne komponente cementa su kalcijum silikati i kalcijum karbonati. Biodentin je pokazao dobre mikromehaniĉke osobine i nisku poroznost koja se odnosi na mikro poroznost ĉija je proseĉna veliĉina pora 92 μm. Kvašenje (Ca=41°), oslobaĊanje jona kalcijuma (0,098 μg/cm²) i pH rastvora gde je ĉuvan (9.07) pokazali su zadovoljavajuće karakteristike. Ćelije su pokazale blizak kontakt sa cementnim ĉesticama što ukazuje na njihovu dobru biokompatibilnost. Zakljuĉak. Biodentin pokazuje dobre mehaniĉke i fiziĉkohemijske karakteristike, ali poseduje nezadovoljavajući radiografski kontrast. Kljuĉne reĉi: biodentin; kalcijum silikat; dentalni cement; referentna taĉka za indentaciju, mikrokompjuterizovana...

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MTA versus Biodentine: Review of Literature with a Comparative Analysis

Cited by 166 publications

References 56 publications

Bio-Inductive Materials in Direct and Indirect Pulp Capping—A Review Article

Bio-Inductive Materials in Direct and Indirect Pulp Capping—A Review Article

Analysis of the Activity and Expression of Cyclooxygenases COX1 and COX2 in THP-1 Monocytes and Macrophages Cultured with BiodentineTM Silicate Cement

The advantages and disadvantages of biodentine: Satisfactory mechanical properties and radiopacity not meeting ISO standard

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