MRT-navigierte stereotaktische Prostatabiopsie

Kuru, Timur H.; Tulea, Corina; Simpfendörfer, Tobias; Popeneciu, Valentín; Roethke, Matthias; Hadaschik, Boris; Hohenfellner, Markus

doi:10.1007/s00120-011-2707-3

Cited by 12 publications

(6 citation statements)

References 29 publications

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“…In a recent small study combining multiparametric MRI with TRUS, Kuru et al. reported a low AUR rate of 2% in 50 men after a median of 24 cores; however, using multiparametric MRI whilst not reducing number of biopsy cores is likely to increase cost. By contrast, our modified technique does not involve routine catheterisation and the 5.2% AUR rate is low.…”

Section: Discussionmentioning

confidence: 99%

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Transperineal template‐guided saturation biopsy using a modified technique: outcome of 270 cases requiring repeat prostate biopsy

et al. 2013

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Objectives• To determine the incidence of prostate cancer (PCa), and pathological grade and location of PCa, using a modified transperineal template-guided saturation biopsy (TTSB).• To compare the acute urinary retention (AUR) rate found using modified TTSB with that of published reports. Patients and Methods• A total of 270 consecutive patients with persistent clinical suspicion of PCa, despite a median (range) of 2 (1-6) sets of negative transrectal ultrasonography-guided biopsies, were enrolled and prospectively studied.• All underwent modified TTSB avoiding the peri-urethral area at the base of the prostate under general anaesthesia.• Statistical analysis was performed using binary logistic regression to determine the prebiopsy predictors of PCa and AUR. Results• The median (range) patient age was 64 (43-85) years, with a median (range) prostate-specific antigen (PSA) of 10 (1-114) ng/mL and median (range) prostate volume of 45 (17-106) mL. A mean (range) of 28 (16-43) cores were taken at modified TTSB.• Prostate cancer was diagnosed in 54.8% (Gleason scores 6 in 27.7%, 7 in 43.2%, 8-10 in 29.1% of patients).• The anterior third only was involved in 21%, the middle third in 6.8% and the posterior third in 8.7% of positive cases, although in 75% of positive cases there was some anterior involvement. Comparing uniquely anterior tumours with the 15.5% found uniquely in either the middle or posterior thirds, there was no significant difference between number of positive cores (2 vs 1, P = 0.091), maximum percentage core involvement (30 vs 17.5%, P = 0.315) and maximum tumour length (3.5 vs 2 mm, P = 0.092).• Fourteen patients (5.2%) developed AUR.• On multivariate analysis, PSA density (PSAD) and pre-TTSB PSA predicted PCa diagnosis, whilst prostate volume, prebiopsy PSA and PSAD predicted AUR. Conclusions• Modified TTSB has a high cancer yield, especially in the anterior region, in patients with previously negative histology but onward suspicion of PCa.• The modified TTSB technique provides a low risk of AUR without compromising cancer yield.

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Section: Discussionmentioning

confidence: 99%

“…Nevertheless, catheter dependencies of 38–39% after TTSB have been reported, persisting in 1.6% of patients after 6 days . Others have combined multiparametric MRI and TTSB to minimise the AUR rate …”

Section: Introductionmentioning

confidence: 99%

Transperineal template‐guided saturation biopsy using a modified technique: outcome of 270 cases requiring repeat prostate biopsy

et al. 2013

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“…In fusion US (FUS), real-time US images are simultaneously presented with corresponding images obtained from previously acquired CT or magnetic resonance (MR) images 10 . Reports have indicated that image fusion is valuable in cases of US-guided targeted ablation of liver and prostate tumors 11 12 13 . However, applications of image fusion to examine the musculoskeletal system have rarely been reported.…”

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Feasibility of US-CT image fusion to identify the sources of abnormal vascularization in posterior sacroiliac joints of ankylosing spondylitis patients

Zhu

Liu

et al. 2015

Sci Rep

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Ultrasound (US) can be used to evaluate the inflammatory activity of the sacroiliac joints (SIJs) in ankylosing spondylitis (AS) patients, but to precisely locate the abnormal vascularization observed on color Doppler US (CDUS) was difficult. To address this issue, we performed US and computed tomography (CT) fusion imaging of SIJs with 84 inpatients and 30 controls, and then assessed the sources of abnormal vascularization in the posterior SIJs of AS patients based on the fused images. Several possible factors impacting the fusion process were considered including the lesion classes of SIJ, the skinfold thickness of the sacral region and the cross-sectional levels of the first, second and third posterior sacral foramina. Our data showed high image fusion success rates at the 3 levels in the AS group (97.0%, 87.5% and 79.8%, respectively) and the control group (96.7%, 86.7%, and 86.7%, respectively).The skinfold thickness was identified as the main factor affecting the success rates. The successfully fused images revealed significant differences in the distribution of abnormal vascularization between 3 levels, as detected via CDUS (P = 0.011), which suggested that inflammation occurred in distinct tissues at different levels of the SIJ (intraligamentous inflammation in Regions 1 and 2; intracapsular inflammation in Region 3).

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“…Im Verlauf des stationären Aufenthalts wurde der transurethrale Dauerkatheter wieder entfernt und die Patienten im Anschluss entlassen.Jede Prozedur wurde softwareassistiert mit Hilfe des BiopSee TM Systems (Version 2.1 Medcom GmbH, Darmstadt) durchgeführt. BiopSee TM besteht aus einem Computer mit integrierter Software, sowie einem speziellen Ultraschallkopf zur transrektalen Anwendung, der während der Biopsie am Eingriffstisch fixiert ist und longitudinale und rotatorische Bewegungen zur Erfassung der Prostata zulässt(Kuru et al 2012). Zunächst wurden die transversalen MRT-Aufnahmen (T2 und DWI) in das System eingelesen und suspekte Läsionen, sofern auf Basis des MRT-Befundes vorhanden, eingezeichnet.…”

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“…Im nächsten Schritt erfolgte die Fusion. Mit Hilfe von BiopSee TM kann dabei aus einer Serie von transversalen TRUS-Bildern eine 3D Rekonstruktion der Prostata erstellt werden(Kuru et al 2012). Die eingelesenen MRT-Bilder werden mit dieser 3D Rekonstruktion der Prostata fusioniert(Kuru et al 2012).…”

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Einfluss der klinischen und interventionellen Parameter im Rahmen der mpMRT/TRUS Fusionsbiopsie der Prostata auf die Detektionsrate des Prostatakarzinoms

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MRT-navigierte stereotaktische Prostatabiopsie

Cited by 12 publications

References 29 publications

Transperineal template‐guided saturation biopsy using a modified technique: outcome of 270 cases requiring repeat prostate biopsy

Transperineal template‐guided saturation biopsy using a modified technique: outcome of 270 cases requiring repeat prostate biopsy

Feasibility of US-CT image fusion to identify the sources of abnormal vascularization in posterior sacroiliac joints of ankylosing spondylitis patients

Einfluss der klinischen und interventionellen Parameter im Rahmen der mpMRT/TRUS Fusionsbiopsie der Prostata auf die Detektionsrate des Prostatakarzinoms

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