MRSA Infection in Lower Extremity Wounds

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most frequently isolated bacteria in wound cultures. MRSA has been linked to lengthened wound healing times, an increase in adverse postoperative outcomes, and mortality. This study investigated the incidence of MRSA in lower extremity wounds and examined outcomes associated with MRSA-infected wounds versus non-MRSA-infected wounds. A retrospective study was conducted. Patients with MRSA-infected wounds were compared with those with uninfected wounds in a 1:2 ratio. Demographics, infection, and stay information were collected. Data were analyzed using SPSS 15.0. 51 patients were included (17 with MRSA and 34 without MRSA). Patients with MRSA had increased lengths of stay and a higher incidence of adverse postoperative outcomes compared with non-MRSA patients. An MRSA infection adversely affects a patient's hospital course. Preoperative screening for MRSA and postoperative surveillance should be considered to prevent and eliminate the spread of this virulent bacterium.

Prevalence and factors associated with wound colonization by Staphylococcus spp. and Staphylococcus aureusin hospitalized patients in inland northeastern Brazil: a cross-sectional study

“…Infections with antibiotic-resistant bacteria are associated with prolonged hospitalization, increased morbidity and mortality, and increased healthcare costs [4,5,20]. Investigation of the pattern of infection by Staphylococcus spp.…”

Comparison of Two Non-Invasive Methods of Microbial Analysis in Surgery Practice: Incision Swabbing and the Indirect Imprint Technique

“…The result of cultivation depends on the cultivation methods chosen [13]. Methicillin-resistant S. aureus (MRSA) is one of the most feared pathogens in both acute and chronic wounds [14]. Of course, there exist other pathogens causing surgical site infection, for example b-hemolytic streptococci in S. pyogenes in the lead, gram-negative bacteria, in addition to other pseudomonads, P. aeruginosa, Acinetobacter spp., which are now becoming multi-drug-resistant [15], as well as other intestinal bacilli (Enterobacteriaceae), particularly members of the genera Klebsiella and Proteus.…”

In vitro evaluation of methicillin-resistant and methicillin-sensitive Staphylococcus aureus susceptibility to Saudi honeys

“…Human isolates of methicillin-resistant Staphylococcus aureus (MRSA) are some of the bacteria most frequently involved in wound infections [1]. MRSA infection is associated with a prolonged healing duration, a rise in postoperative complications, and increased mortality [2]. According to a recent meta-analysis report extracted from seven articles, the overall MRSA prevalence in Saudi Arabia is 38%, which is quite high in comparison with Gulf Corporation Council (GCC) countries, with Kuwait having the lowest (3.3%) [3,4].…”