MRI of the pharynx and treatment efficacy of a mandibular advancement device in obstructive sleep apnoea syndrome

Sanner, Bernd; Heise, M.; Knoben, B.; Machnick, M.; Laufer, U.; Kikuth, R.; Zidek, Walter; Hellmich, Bernhard

doi:10.1183/09031936.02.00268902

Cited by 72 publications

(31 citation statements)

References 23 publications

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“…The airway was still open during a Muller manoeuvre and mandibular advancement in good responders compared with a clear collapse in poor responders visualised by nasendoscopy [45]. A previous small study produced similar results by magnetic resonance imaging [57]. A model of the upper airway using combined upper airway imaging and computational fluid dynamics has been used to evaluate the influence of MADs on upper airway volume and resistance and this method has future potential for the prediction of treatment success [48].…”

Section: Prediction Of Treatment Successmentioning

confidence: 51%

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Non-CPAP therapies in obstructive sleep apnoea: mandibular advancement device therapy

Marklund¹,

Verbraecken²,

Randerath³

2011

Eur Respir J

166

136

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Mandibular advancement devices (MADs) represent the main non-continuous positive airway pressure (non-CPAP) therapy for patients with obstructive sleep apnoea (OSA). The aim of the European Respiratory Society Task Force was to review the evidence in favour of MAD therapy. Effects of tongue-retaining devices are not included in this report.Custom-made MADs reduce apnoea/hypopnoea index (AHI) and daytime sleepiness compared with placebo devices. CPAP more effectively diminishes AHI, while increasing data suggest fairly similar outcomes in relation to symptoms and cardiovascular health from these treatments. Patients often prefer MADs to CPAP. Milder cases and patients with a proven increase in upper airway size as a result of mandibular advancement are most likely to experience treatment success with MADs. A custom-made device titrated from an initial 50% of maximum mandibular advancement has been recommended. More research is needed to define the patients who will benefit from MAD treatment compared with CPAP, in terms of the effects on sleep-disordered breathing and on other diseases related to OSA.In conclusion, MADs are recommended for patients with mild to moderate OSA (Recommendation Level A) and for those who do not tolerate CPAP. The treatment must be followed up and the device adjusted or exchanged in relation to the outcome.

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Section: Prediction Of Treatment Successmentioning

confidence: 51%

“…In addition, 21 further clinical trials that highlighted particular aspects of MAD treatment, such as the mechanisms of action and prediction of treatment outcome, were identified [1][2][3][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61]. A table is available in the online supplementary material.…”

Section: Search Criteriamentioning

confidence: 99%

Non-CPAP therapies in obstructive sleep apnoea: mandibular advancement device therapy

Marklund¹,

Verbraecken²,

Randerath³

2011

Eur Respir J

166

136

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show abstract

“…Patients who refused CPAP therapy were offered a mandibular advancement device (for details see [12]) or a "conservative treatment" (sleep hygiene and dietetic measures).…”

Section: Polysomnographymentioning

confidence: 99%

Influence of treatment on leptin levels in patients with obstructive sleep apnoea

Sanner¹,

Kollhosser²,

Buechner³

et al. 2004

European Respiratory Journal

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“…oraz Sanner i wsp. 31,43,44 Istnieją także doniesienia przedstawiające zależność efektywności leczenia i stopnia nasilenia OBS. Badania Hoffsteina, porównujące skuteczność terapii OBS aparatami wewnątrzustnymi i CPAP wskazują na lepszą skuteczność leczenia z zastosowaniem CPAP.…”

Section: T H I S C O P Y I S F O R P E R S O N a L U S E O N L Y -D Iunclassified

Obstructive sleep apnea: Aetiology, diagnosis, treatment

Wojda¹,

Kostrzewa-Janicka²

2015

Protet Stomatol

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MRI of the pharynx and treatment efficacy of a mandibular advancement device in obstructive sleep apnoea syndrome

Cited by 72 publications

References 23 publications

Non-CPAP therapies in obstructive sleep apnoea: mandibular advancement device therapy

Non-CPAP therapies in obstructive sleep apnoea: mandibular advancement device therapy

Influence of treatment on leptin levels in patients with obstructive sleep apnoea

Obstructive sleep apnea: Aetiology, diagnosis, treatment

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