2013
DOI: 10.1016/j.jmr.2013.01.011
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MRI of fast-relaxing spins

Michael Garwood

Abstract: MR imaging of extremely fast-relaxing spins is currently a topic of much interest due to recent technical innovations and groundbreaking studies demonstrating its utility in biomedical research applications. From a technical perspective, this article examines the different classes of pulse sequences currently available to image spins with ultra-short transverse relaxation times (T2 and T2*), with particular attention focused on the newest member of the class, sweep imaging with Fourier transformation (SWIFT).

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Cited by 23 publications
(13 citation statements)
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“…Three NMR pulse sequences were used to measure the saturation of the rock core: single‐pulse free induction decay (FID), zero echo time 1‐D imaging (ZTE), and Carr‐Purcell‐Meiboom‐Gill (CPMG) 1‐D T 2 relaxation [ Callaghan , ; Garwood , ; Weiger et al ., ]. The NMR signal is detected for the 1 H protons so is not sensitive to CO 2 , air, fluorine, or any solid parts of the sample.…”
Section: Experimental Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…Three NMR pulse sequences were used to measure the saturation of the rock core: single‐pulse free induction decay (FID), zero echo time 1‐D imaging (ZTE), and Carr‐Purcell‐Meiboom‐Gill (CPMG) 1‐D T 2 relaxation [ Callaghan , ; Garwood , ; Weiger et al ., ]. The NMR signal is detected for the 1 H protons so is not sensitive to CO 2 , air, fluorine, or any solid parts of the sample.…”
Section: Experimental Methodsmentioning
confidence: 99%
“…The ZTE imaging sequence [ Garwood , ; Weiger et al ., ], depicted in Figure , has been specifically designed to allow the imaging of fast relaxing NMR signals of short T 2 values. This is achieved by switching on a readout gradient before any RF pulse excitation.…”
Section: Experimental Methodsmentioning
confidence: 99%
“…In interleaved sequences, signals decaying more rapidly than the system dead times cannot be detected, whereas CEA continuously monitors the MR signal even during RF excitation. Thus, tightly bounded water in bone, for example, is not visible with interleaved NMR approaches [13][14][15][16][17], and new contrast mechanisms and novel sequences may be developed with further research on CEA.…”
Section: Methodsmentioning
confidence: 99%
“…In recent years, several techniques classified as zero and ultrashort echo time (ZTE and UTE, respectively) imaging as well as sweep imaging with Fourier transformation (SWIFT) methods have been developed to target short T 2 protons . Depending on the T 2 domain of the protons of interest different approaches are used.…”
Section: Introductionmentioning
confidence: 99%