MRI-informed machine learning-driven brain age models for classifying mild cognitive impairment converters
Hanna Lu,
Jing Li
Abstract:BACKGROUND Brain age model, including estimated brain age and brain-predicted age difference (brain-PAD), has shown great potentials for serving as imaging markers for monitoring normal ageing, as well as for identifying the individuals in the pre-diagnostic phase of neurodegenerative diseases. PURPOSE This study aimed to investigate the brain age models in normal ageing and mild cognitive impairments (MCI) converters and their values in classifying MCI conversion. METHODS Pre-trained brain age model was const… Show more
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