MRI-Guided Derivation of the Input Function for PET Kinetic Modeling

Richard, Marie Anne; Fouquet, Jérémie P.; Lebel, Réjean; Lepage, Martin

doi:10.1016/j.cpet.2015.09.003

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“…Other studies [123,124] demonstrated that PVC enhances the availability of detecting changes in amyloid deposition. Further applications for PVC in PET/MRI focus on image-derived input functions (IDIF) in neurological disorders [125] or PVC for improved quantifica-tion of PET uptake in atherosclerotic plaques in the aortic and carotid arteries [126][127][128]. Especially in the latter, PVC is of particular importance as relative changes of the PET uptake values by > 50% can occur due to the small size of the plaques [126].…”

Section: Partial Volume Correctionmentioning

confidence: 99%