MRI-guided core needle biopsy of the prostate: acceptance and side effects

Egbers, Nina; Schwenke, Carsten; Maxeiner, Andreas; Teichgräber, Ulf; Franiel, Tobias

doi:10.5152/dir.2014.14372

Cited by 29 publications

(39 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Only 41 % of respondents were advised by their physician about the possibility of an MRI and MRI-guided biopsy after a negative TRUS biopsy, despite higher detection rates, reduced histological upgrading, and the possibility to rule out clinically significant tumors; in comparison to TRUS-GB, no increased side effects or complications have been demonstrated, and patients have shown good acceptance of the procedure [28,29].…”

Section: Discussionmentioning

confidence: 99%

Current Utilization and Acceptance of Multiparametric MRI in the Diagnosis of Prostate Cancer. A Regional Survey

Ullrich

Schimmöller

Oymanns

et al. 2017

Fortschr Röntgenstr

View full text Add to dashboard Cite

/2 11/8 11 77 54 Fax: ++ 49/2 11/8 11 61 45 lars.schimmoeller@med.uni-duesseldorf.de ABSTR AC TPurpose To assess the current regional acceptance, valuation, and clinical role of multiparametric MRI (mp-MRI) in prostate cancer diagnostics by patients and physicians. Materials and MethodsOf 482 distributed standardized questionnaires, 328 patient and 31 physician questionnaires (urological and general practitioners in and around Düssel-dorf) were analyzed over a period of 11 months. Questions were asked concerning general knowledge about prostate cancer, current diagnostic procedures, and knowledge about mp-MRI and MRI-guided biopsy.Results 70 % of the patients regarded accurate and exact diagnostics of prostate carcinomas as very important and 68 % considered MP-MRI a useful technique. 28 % of the patients with elevated PSA levels and negative transrectal ultrasound-guided biopsy (TRUS-GB) received MP-MRI as a secondary diagnostic. More than half of the patients estimated their overall knowledge about prostate cancer mediocre or worse and wished for more information about MR diagnostics. The majority of physicians (55 %) ordered MP-MRI studies of the prostate and 68 % saw their basic role in secondary diagnostics.Conclusion In this regional assessment mp-MRI of the prostate was considered useful by patients and practitioners. Currently, there still is a considerable discrepancy between recommended and the actual number of conducted MP-MRI studies, particularly in patients after previous negative TRUS-GB, although practitioners already see the benefit in this patient collective. Even though the use of prostate MRI is frequently more established than suggested in the current German S3-guideline, its full potential has not yet been exploited. More comprehensive information about the applications and diagnostic benefits of prostate MRI is needed and desired among patients and physicians.

show abstract

Section: Discussionmentioning

confidence: 99%

Current Utilization and Acceptance of Multiparametric MRI in the Diagnosis of Prostate Cancer. A Regional Survey

Ullrich

Schimmöller

Oymanns

et al. 2017

Fortschr Röntgenstr

View full text Add to dashboard Cite

show abstract

“…Similarly, Pepe et al found that hematospermia significantly correlated with the number of cores following transperineal PB (30.4% and 10.7% following >/=24 cores vs. 12 cores, respectively; p=0.001) 10 . Conversely, in a recent MRI in-bore PB series with a median of 4 cores, the rate of hematospermia was similar to TRUS-guided prostate biopsies with 10 median cores (36% vs. 33%, p>0.05) 14 .…”

Section: Hematospermiamentioning

confidence: 99%

“…In this TRUS-guided series, only 0.6% of patients experienced prolonged hematochezia or required surgical intervention for bleeding control, with no significant correlation with the number of cores taken 5 . The occurrence of hematochezia after MRI in-bore prostate biopsy ranged from 11% to 17% 3 , with no significant advantages offered by this approach over traditional TRUS-guided PB in terms of incidence and duration of bleeding in this population 14 . Massive rectal bleeding is uncommon and management options include rectal balloon tamponade, endoscopic adrenaline injection or sclerotherapy, or direct endoscopic vessel clipping or ligation 1 .…”

Section: Rectal Bleedingmentioning

confidence: 99%

“…MRI-guided in-bore prostate biopsies have been associated with lower rates of overall complications compared to TRUS-guided PB, including bleeding. Egbers et al, in a prospective non-randomized study of 54 patients, recently reported hematuria in 51% of MRI-guided in-bore biopsy compared to 79% of transrectal PB (p=0.006), as well as a longer bleeding duration for the latter technique 14 . Moreover, a recent systematic review evaluating outcomes of MRI in-bore PB performed transrectally, transient hematuria occurred in 1%-24% of patients 3 .…”

Section: Hematuriamentioning

confidence: 99%

“…There are limited data on the impact of serial biopsies during active surveillance (AS) on voiding symptoms and risk of acute urinary retention, although limited evidence suggests no significant correlation between number of prostate biopsies and IPSS 28 . Based on the currently available data, the reported incidence of acute urinary retention after MRI-guided PB is sporadic, from 0% to 1% 3,14,29 .…”

Section: Lower Urinary Symptoms and Acute Urinary Retentionmentioning

confidence: 99%

See 2 more Smart Citations

Complications After Systematic, Random, and Image-guided Prostate Biopsy

et al. 2017

View full text Add to dashboard Cite

Evidence Synthesis: The most frequent complication after PB is minor and self-limiting bleeding (hematuria and hematospermia), irrespective of the biopsy approach. Occurrence of rectal bleeding was comparable among traditional TRUS-guided and image-guided PB. Almost 25% of patients experience lower urinary tract symptoms, but only a few have urinary retention, with higher rates after transperineal approach. Temporary erectile dysfunction is not negligible, with a return to baseline after 1-6 months. The incidence of infective complications is being increasing, with higher rates among men with medical comorbidities and older age. Transperineal and in-bore MRI targeted biopsy may reduce the risk of severe infectious complications. Mortality after PB is uncommon, irrespective of biopsy technique. Conclusions:Complications after PB are frequent but often self-limiting. The incidence of hospitalization due to severe infections is continuously increasing. Still, a careful appraisal of 3 patient's general health status, risk factors and likelihood of antimicrobial resistance should be done before scheduling a PB. Patient Summary:In this paper we reviewed the variety and incidence of complications after prostate biopsy. Even if frequent, seldom represent a problem for the patient. The most troublesome complications are infections. In order to minimize this risk, a careful evaluation of patient's medical condition must be done before biopsy.4

show abstract

Comparison of Multiparametric Magnetic Resonance Imaging and Targeted Biopsy With Systematic Biopsy Alone for the Diagnosis of Prostate Cancer

et al. 2019

View full text Add to dashboard Cite

Key Points Question Is prebiopsy magnetic resonance imaging combined with targeted biopsy associated with improved detection of clinically significant prostate cancer compared with transrectal ultrasonography–guided systematic prostate biopsy alone? Findings This systematic review and meta-analysis of 7 randomized clinical trials (2582 patients) demonstrates that prebiopsy magnetic resonance imaging combined with targeted biopsy is associated with improved detection of clinically significant prostate cancer and reduced numbers of biopsy cores per procedure, while potentially avoiding unnecessary biopsies. Meaning These findings support the introduction of prebiopsy magnetic resonance imaging into the diagnostic pathway for biopsy-naive men with suspected prostate cancer.

show abstract

MRI-guided core needle biopsy of the prostate: acceptance and side effects

Cited by 29 publications

References 15 publications

Current Utilization and Acceptance of Multiparametric MRI in the Diagnosis of Prostate Cancer. A Regional Survey

Current Utilization and Acceptance of Multiparametric MRI in the Diagnosis of Prostate Cancer. A Regional Survey

Complications After Systematic, Random, and Image-guided Prostate Biopsy

Comparison of Multiparametric Magnetic Resonance Imaging and Targeted Biopsy With Systematic Biopsy Alone for the Diagnosis of Prostate Cancer

Contact Info

Product

Resources

About