MRI features of perianal fistulas: is there a difference between Crohn’s and non-Crohn’s patients?

Oliveira, Irai S.; Kilcoyne, Aoife; Price, Max; Harisinghani, Mukesh G.

doi:10.1007/s00261-016-0989-z

Cited by 9 publications

(3 citation statements)

References 19 publications

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“…By analyzing our patients, we found that 61.0% (83/136) presented with complex fistulas, whereas high fistulas were uncommon, only 8.1% (11/136). Oliveira et al showed that the characteristics of perianal fistulas were actually similar in the CD and non-CD populations, as evidenced by abscess incidence, volume, and signs of fistula activity (high signal on T2WI images as well as focal enhancement); however, they also found that compared to the non-CD population, the CD population was younger (28.6 ± 14.9 y vs. 42.4 ± 14.7 y) and rectal inflammation was more common (30.2% vs. 6.7%) [ 35 ]. The mean age of our patients was 27.5 ± 10.2 years and the incidence of rectal involvement was 34.6% (47/136), similar to the CD population of Oliveira et al ( p = 0.51 and 0.49, respectively).…”

Section: Discussionmentioning

confidence: 99%

The relationship between perianal fistula activity and abdominal adipose tissue in Crohn’s disease: an observational study

et al. 2022

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Objective The aim of this study was to analyze the relationship between abdominal adipose tissue and perianal fistula activity in patients with Crohn's disease (CD) using cross-sectional imaging. Methods Patients with perianal fistulizing CD who underwent pelvic magnetic resonance imaging (MRI) and abdominal computed tomography (CT) were retrospectively enrolled. We scored the fistulas in each patient's MRI images based on Van Assche's classification. The area and density of subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) (at the third, fourth, and fifth lumbar (L3, L4, and L5) levels were measured by averaging five slices of measurements at each vertebral level in CT images, and areas were further standardized by the lumbar height2 (heightL1-5). The VAT/SAT ratio (VSR) and VAT/Total adipose tissue (VA/TA) index were calculated. Based on MRI scores, patients were divided into two groups with low and high activity, and their clinical, MRI features, and CT parameters were compared. We evaluated patients with follow-up MRI and compared the differences in clinical and radiological indicators among patients with different outcomes. Results Overall, 136 patients were included, 77 in the low-activity group and 59 in the high-activity group. Patients in the high activity group had lower subcutaneous adipose index (all levels, p < 0.05) and visceral adipose index (L3 level, p < 0.01), but higher SAT and VAT density (all levels, p < 0.01), VSR (L5 level, p = 0.07) and VA/TA index (L5 level, p < 0.05). Conclusion There were differences in adipose tissue composition among CD patients with different active perianal fistulas.

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Section: Discussionmentioning

confidence: 99%

The relationship between perianal fistula activity and abdominal adipose tissue in Crohn’s disease: an observational study

et al. 2022

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“…Perianal abscess is caused by infection of the anal gland located between the sphincter muscles. e ways of infection include blockage of the anal glands, inability to drain the secretion of the anal glands, fluid accumulation in the glands, infection of the anal glands (between the sphincter muscles), the formation of swelling (infection source), and spread along with the conjoint longitudinal muscle to the perianal space [4]. e diagnosis of perianal abscess and anal canal stenosis is clear before surgery, and the location of the perianal opening, abscess range, anal fistula trend, and its relationship with surrounding muscle tissue are clearly defined, which is of great significance for the selection of surgical methods and the protection of anal physiological functions [5,6].…”

Section: Introductionmentioning

confidence: 99%

Deep Learning-Based Magnetic Resonance Imaging Features in Diagnosis of Perianal Abscess and Fistula Formation

Han

2021

Contrast Media & Molecular Imaging

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There was an investigation of the diagnostic and prognostic effect of magnetic resonance imaging (MRI) based on multimodal feature fusion algorithm for impotence of perianal abscess. In this study, the second to fifth convolution blocks of the visual geometric group network were applied to extract the depth features in the way of transfer learning, and a multimode feature fusion algorithm was constructed. The whole network was trained by maximizing the energy proportion of the feature layers, which was compared with the fully convolutional neural network (FCN) algorithm. Then, this algorithm was adopted to the imaging diagnosis of 50 patients with anorectal diseases admitted to our hospital, and it was found that the similarity coefficient (85.37%), accuracy (80.02%), and recall rate (79.38%) of the improved deep learning algorithm were higher markedly than those of the FCN algorithm (70.18%, 67.82%, and 66.92%) ( P < 0.05 ). As the number of convolutional layers increased, the segmentation accuracy of the convolutional neural network (CNN) algorithm was also improved. The detection rate of the observation group (84%) rose hugely compared with the control group (64%), and the difference was statistically obvious ( P < 0.05 ). Besides, the detection accuracy of abscess location (84%), impotent tract location (80%), and internal orifice location (92%) in patients from the observation group was higher substantially than the accuracy of abscess location (60%), impotent tract location (68%), and internal orifice location (72%) from the control group ( P < 0.05 ). In conclusion, the performance of the multimodal feature fusion algorithm was better, and the MRI image feature analysis based on this algorithm had a higher diagnostic accuracy, which had a positive effect on improving the detection rate, detection accuracy, and disease classification.

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“…Hence, MRE is generally preferred over CT to limit the increased risk of cancer in patients with CD. Additionally, MRE has been shown to be the most sensitive technique for detecting active disease, the perianal complications, and bowel wall fibrosis 4–6 . However, the administration of gadolinium should be kept in mind in patients requiring frequent MRE examination to preclude tissue deposition and the development of nephrogenic systemic fibrosis.…”

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confidence: 99%

Editorial for “Novel Associations Between Genome‐Wide Single Nucleotide Polymorphisms and MR Enterograpy Features in Crohn's Disease Patients”

Kahraman

2020

Magnetic Resonance Imaging

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MRI features of perianal fistulas: is there a difference between Crohn’s and non-Crohn’s patients?

Cited by 9 publications

References 19 publications

The relationship between perianal fistula activity and abdominal adipose tissue in Crohn’s disease: an observational study

The relationship between perianal fistula activity and abdominal adipose tissue in Crohn’s disease: an observational study

Deep Learning-Based Magnetic Resonance Imaging Features in Diagnosis of Perianal Abscess and Fistula Formation

Editorial for “Novel Associations Between Genome‐Wide Single Nucleotide Polymorphisms and MR Enterograpy Features in Crohn's Disease Patients”

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