MRI‐based morphometric analysis of typical and atypical brain development

Kennedy, David N.; Haselgrove, Christian; McInerney, Sean C.

doi:10.1002/mrdd.10075

Cited by 24 publications

(15 citation statements)

References 48 publications

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“…Other studies have investigated gross anatomical structural differences in brain morphology as a potential biological phenotype for dyslexia (see Kennedy et al, [2003] in this issue for overview of MRI and its use in morphometry studies of development). Several early publications reported that dyslexia is marked by a lack of the normal asymmetry in planum temporale, which might serve as such a phenotypic marker [Galaburda et al, 1985;Rumsey et al, 1986].…”

Section: Anatomical Contributionsmentioning

confidence: 98%

The development of reading impairment: A cognitive neuroscience model

McCandliss

Noble

2003

Ment. Retard. Dev. Disabil. Res. Rev.

228

152

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This review discusses recent cognitive neuroscience investigations into the biological bases of developmental dyslexia, a common disorder impacting approximately 5 to 17 percent of the population. Our aim is to summarize central findings from several lines of evidence that converge on pivotal aspects of the brain bases of developmental dyslexia. We highlight ways in which the approaches and methodologies of developmental cognitive neuroscience that are addressed in this special issue-including neuroimaging, human genetics, refinement of cognitive and biological phenotypes, neural plasticity and computational model-can be employed in uncovering the biological bases of this disorder. Taking a developmental perspective on the biological bases of dyslexia, we propose a simple cascading model for the developmental progression of this disorder, in which individual differences in brain areas associated with phonological processing might influence the specialization of visual areas involved in the rapid processing of written words. We also discuss recent efforts to understand the impact of successful reading interventions in terms of changes within cortical circuits associated with reading ability.

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Section: Anatomical Contributionsmentioning

confidence: 98%

The development of reading impairment: A cognitive neuroscience model

McCandliss

Noble

2003

Ment. Retard. Dev. Disabil. Res. Rev.

228

152

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“…Therefore, MRI has also provided an opportunity to investigate healthy children and thereby has markedly improved data about normal brain development (Kennedy, Haselgrove, & McInerney, 2003).…”

Section: Mri As a Neuroimaging Technique In Childhoodmentioning

confidence: 99%

Structural and functional MRI‐ findings in children and adolescents with antisocial behavior

Vloet

Konrad²,

Huebner³

et al. 2008

Behavioral Sci & The Law

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We describe the developmental taxonomy of children with CD and focus on those with the early onset subtype. Structural MRI data of these children and antisocial adults are recapitulated. The impact of investigating neurobiological underpinnings of antisocial behavior and how this might contribute to future forensic and psychiatric assessments is discussed. RESULTS/ CONCLUSION: Children display similar structural aberrations of fronto-limbic structures to adults with antisocial behavior, and amygdala dysfunction might be closely related to dysregulated emotions. Though the investigation of biological factors in antisocial subjects has made great progress in recent years, today MRI is still a rather complex, expensive and indistinct method for forensic assessment.

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“…In general researchers collect at least one set of structural images to allow localization of the functional activations. In our lab we collect a high resolution 3D volume [for anatomical studies similar to those described in Kennedy et al, 2003, in this issue] as well as a set of in-plane images that cover the whole brain and that are used for localizing the functional activity. For the functional data collection, imaging tasks typically are organized into a number of discrete 'runs' with rest breaks in between.…”

Section: Paradigm Developmentmentioning

confidence: 99%

Imaging the developing brain with fMRI

Davidson

Thomas

Casey

2003

Ment. Retard. Dev. Disabil. Res. Rev.

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Advancements in magnetic imaging techniques have revolutionized our ability to study the developing human brain in vivo. The ability to noninvasively image both anatomy and function in healthy volunteers, including young children, has already enhanced our understanding of brain and behavior relations. The application of these techniques to developmental research offers the opportunity to further explore these relationships and allows us to ask questions about where, when and how cognitive abilities develop in relation to changes in underlying brain systems. It is also possible to explore the contributions of maturation versus learning in the development of these abilities through cross-sectional and longitudinal research involving training and intervention procedures. Current imaging methodologies, in conjunction with new and rapidly evolving techniques, hold the promise of even greater insights into developmental issues in the near future. These methodologies and their application to development and learning are discussed in the current paper.

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MRI‐based morphometric analysis of typical and atypical brain development

Cited by 24 publications

References 48 publications

The development of reading impairment: A cognitive neuroscience model

The development of reading impairment: A cognitive neuroscience model

Structural and functional MRI‐ findings in children and adolescents with antisocial behavior

Imaging the developing brain with fMRI

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