MRI and CT findings of neurohypophyseal germinoma

Abstract

Infundibular thickening, absence of the posterior pituitary high signal on T1-weighted image, lack of calcification and hyperdensity on unenhanced CT are common imaging features of neurohypophyseal germinoma.

Unusual cause of profound weight loss in a young woman

“…A delay in diagnosis is seen in significant proportion of patients, particularly in malignant suprasellar germinomas and the index case is a befitting example 2–4. CEMRI features of isointense to hypointense on T1-weighted and isointense to hyperintense on T2-weighted imaging with intense contrast enhancement can be associated with meningioma, gliomas, intracranial lymphoma, lymphocytic hypophysitis or granular cell tumours 6. Hence, a histopathological diagnosis is a must to initiate on appropriate therapy, as was performed in the present case clinching the diagnosis.…”

A 40‐year‐old Woman With a Progressive Periventricular White Matter Lesion

“…In this case, the characteristic radiological features of a germinoma were absent (3, 5). There was no mass effect, that is, compression of pre‐existent anatomical structures by growth of a solid tumor, and no enhancement after gadolinium administration.…”

Pretreatment Diagnosis of Suprasellar Papillary Craniopharyngioma and Germ Cell Tumors of Adult Patients

“…5,17 This infundibular lesion can extend vertically into the sellar region along the pituitary stalk axis (Figs 3A, 4A, -B, and 5C). The pineal region is the most common location for GCTs, accounting for 40%-60%.…”

“…However, the treatment and outcomes of both tumor types are quite different. 2,4,5 Surgical resection not only is the main treatment of PCPs but also remarkably affects the outcome. 6 By contrast, complete surgical resection is usually unnecessary in patients with germinoma.…”