MRgFUS treatment of superficial osteoid osteomas of the lower limbs

Bazzocchi, Alberto; Napoli, Alessandro; Filonzi, Giacomo; Facchini, Giancarlo; Spinnato, Paolo; Busacca, Maurizio; Catalano, Carlo; Albisinni, Ugo

doi:10.1186/2050-5736-3-s1-o45

Cited by 3 publications

(6 citation statements)

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“…Several authors inferred that skin burns were most likely due to lack of operator experience or not following established protocols. The lack of adverse events in some studies [17,37,47,48,50,54,55] may relate to the limited number of patients. In clinical studies with large number of patients, an USgFUS study [19] reported a major complication rate of 28% (22/80) for patients with primary malignant tumors.…”

Section: Safetymentioning

confidence: 99%

Focused ultrasound for treatment of bone tumours

Rodrigues

Stauffer

Vrba

et al. 2015

International Journal of Hyperthermia

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Section: Safetymentioning

confidence: 99%

Focused ultrasound for treatment of bone tumours

Rodrigues

Stauffer

Vrba

et al. 2015

International Journal of Hyperthermia

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“…In this scenario, a novel radiation-free technique of thermal ablation is represented by magnetic resonance-guided focused ultrasound surgery (MRgFUS) that is reported to have similarly high rates of success and nearly no complications [ 6 , 25 , 26 ]. Furthermore, MRgFUS allows for avoidance of partial treatments encountered with CT-RFA due to inaccurate needle positioning [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

“…Acoustic attenuation in bone is 30–60 times higher than in soft tissue; therefore, the lesions that benefit from MRgFUS are the most superficial ones [ 26 ]. Lesions deep in the bone more than few millimeters are not suitable to be treated directly [ 29 ].…”

Section: Introductionmentioning

confidence: 99%

“…Another important factor is the distance of the lesion from the skin surface, because due to the interposition of soft tissues, it is possible that the US beam loses its effectiveness. If the distance between the skin surface and the target lesion exceeds 10 cm, the ablation can be compromised [ 26 ].…”

Section: Introductionmentioning

confidence: 99%

“…Another crucial aspect in planning MRgFUS is patient positioning, as it allows the US beam to optimally reach the target area. It is important that the skin above the lesion is in close contact with the transducer [ 26 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Needleless Ablation of Osteoid Osteoma and Osteoblastoma: The Emergent Role of MRgFUS

Bellisari

Palumbo²,

Masciocchi

et al. 2021

JCM

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Osteoblastoma (OB) and osteoid osteoma (OO) are benign bone-forming tumors, with nearly identical basic microscopic features. The main difference is dimension (OO has usually a nidus measuring <2 cm in diameter). In addition, OB is biologically more active than OO, with a tendency to grow in size. Historically, treatments have included surgical resection and analgesics, although invasiveness and poor tolerance have led to the current standard of care moving toward interventional radiology, where radiofrequency ablation (RFA) represents the most diffuse technique. Magnetic resonance-guided focused ultrasound surgery (MRgFUS) has recently emerged as another innovative alternative treatment, providing tumor ablation through a needleless and ionizing radiation-free modality. In addition, this technique has the ability to guarantee a very precise and controlled increase in temperature, delivering small amounts of energy that can accurately destroy only the lesion, avoiding healthy surrounding tissues. The present review focuses on MRgFUS as the less invasive, safe, effective, and durable treatment option for the management of osteoid osteoma and osteoblastoma, including a description of technical details, indications and outcomes.

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