MR urography: the future gold standard in paediatric urogenital imaging?

Borthne, Arne; Nordshus, T; Reiseter, Tor; Geitung, Jonn Terje; Gjesdal, Kjell-Inge; Babovic, Almira; Bjerre, Anna; Loe, Borger

doi:10.1007/s002470050677

Cited by 95 publications

(36 citation statements)

References 30 publications

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“…Use of MR urography to obtain both anatomic and functional information in a single examination without radiation would be beneficial, especially for follow-up in young patients (13,16,18). The purpose of this large, multicenter study was to evaluate whether DCE MR urography is equivalent to RS for the measurement of SRF in patients suspected of having chronic and intermittent urinary obstruction.…”

Section: Settings and Participantsmentioning

confidence: 99%

Chronic Urinary Obstruction: Evaluation of Dynamic Contrast-enhanced MR Urography for Measurement of Split Renal Function

Claudon¹,

Durand²,

Grenier³

et al. 2014

Radiology

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).q RSNA, 2014 Purpose:To evaluate if measurement of split renal function (SRF) with dynamic contrast material-enhanced (DCE) magnetic resonance (MR) urography is equivalent to that with renal scintigraphy (RS) in patients suspected of having chronic urinary obstruction. Materials and Methods:The study protocol was approved by the institutional ethics committee of the coordinating center on behalf of all participating centers. Informed consent was obtained from all adult patients or both parents of children. This prospective, comparative study included 369 pediatric and adult patients from 14 university hospitals who were suspected of having chronic or intermittent urinary obstruction, and data from 295 patients with complete data were used for analysis. SRF was measured by using the area under the curve and the Patlak-Rutland methods, including successive review by a senior and an expert reviewer and measurement of intra-and interobserver agreement for each technique. An equivalence test for mean SRF was conducted with an a of 5%. Results:Reproducibility was substantial to almost perfect for both methods. Equivalence of DCE MR urography and RS for measurement of SRF was shown in patients with moderately dilated kidneys (P , .001 with the Patlak-Rutland method). However, in severely dilated kidneys, the mean SRF measurement was underestimated by 4% when DCE MR urography was used compared with that when RS was used. Age and type of MR imaging device had no significant effect. Conclusion:For moderately dilated kidneys, equivalence of DCE MR urography to RS was shown, with a standard deviation of approximately 12% between the techniques, making substitution of DCE MR urography for RS acceptable. For severely dilated kidneys, a mean underestimation of SRF of 4% should be expected with DCE MR urography, making substitution questionable.q RSNA, 2014

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Section: Settings and Participantsmentioning

confidence: 99%

Chronic Urinary Obstruction: Evaluation of Dynamic Contrast-enhanced MR Urography for Measurement of Split Renal Function

Claudon¹,

Durand²,

Grenier³

et al. 2014

Radiology

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“…If this test is not available, then intravenous urography (IVU) is an alternative examination performed at the age 1±3 months. A recent study [4] has shown that MR urography (MRU) with a prolonged contrast-enhanced dynamic technique and furosemide provocation has the potential to replace traditional diagnostic methods which use ionizing radiation in pediatric patients. Magnetic resonance urography was found to be equal to, or better than, scintigraphy and IVU in predicting urinary obstruction, particularly PUJ obstruction, independent of renal function.…”

Section: Urinary Tract Dilatation (Hydronephrosis)mentioning

confidence: 99%

The gamut of abdominal and pelvic cystic masses in children

et al. 2001

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The gamut of abdominal and pelvic cystic masses in children is long with lesions affecting the urogenital tract and retroperitoneum, gastrointestinal tract and mesentery, hepatobiliary tract, and spleen. The goal of this pictorial review is to display the radiological manifestations of these disorders. The radiologist will learn, from this review of the differential diagnosis, how to reach a diagnosis after analyzing the characteristic findings using the appropriate imaging diagnostic studies among the various modalities available in his armamentarium, and the optimal management of these conditions.

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“…With special sequences it is possible to yield a magnetic resonance urogram (MRU) comparable to the IVU in terms of anatomical detail. MRU can be performed independently of the renal function 5 .…”

Section: Magnetic Resonance Imaging (Mri)mentioning

confidence: 99%